My Sweet Audrina is a 1982 novel by V. C. Andrews. It was the only stand-alone novel published during Andrews' lifetime and was a number-one best-selling novel in North America. The story takes place in the Mid-Atlantic United States during the 1960s and 1970s. The story features diverse subjects, such as brittle bone disease, rape, posttraumatic stress disorder and diabetes, in the haunting setting of a Victorian-era mansion near the fictitious River Lyle.