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The coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes.
The transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
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Subjects
Virus T-lymphotrope 1 humain, HTLV (Viruses), Transcriptional Activation, Genetics, Virus de l'immunodéficience humaine, Rétrovirus, HIV (Viruses), Pathogenität, Transactivateurs, Microbiology, Transcription génétique, Infections à rétrovirus, Retrovirus infections, Viral Gene Expression Regulation, Deltarétrovirus, Genregulation, Retroviren, Régulation de l'expression des gènes des virus, Genoom, Génétique, Expression génique, Retrovirussen, Mensch, Retroviridae Infections, Retroviridae, Retroviruses, Genexpressie, VIH-1, Protéines des Retroviridae, Acquired Immunodeficiency Syndrome, Transkriptionsfaktor, HIV-1, Human T-lymphotropic virus 1, Retroviridae Proteins, Trans-ActivatorsShowing 2 featured editions. View all 2 editions?
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1
Transacting Functions Of Human Retroviruses (Current Topics in Microbiology & Immunology)
1995, Springer
Hardcover
in English
- 1 edition
038757901X 9780387579016
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Libraries near you:
WorldCat
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2
Transacting functions of human retroviruses
1995, Springer-Verlag
in English
038757901X 9780387579016
|
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Libraries near you:
WorldCat
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- Created November 2, 2008
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July 30, 2019 | Edited by MARC Bot | associate edition with work OL9335926W |
April 16, 2010 | Edited by bgimpertBot | Added goodreads ID. |
November 2, 2008 | Created by ImportBot | Imported from Talis record |