This publication is a call to action to governments and donors to sustain and increase funding for immunization in order to build upon the progress made so far in meeting the global goals. It focuses on the major developments in vaccines and immunization since 2000. Part 1 examines the impact of immunization on efforts to meet the Millennium Development Goals, especially the goal to reduce deaths among children under five. It looks at the development and use of vaccines and at the safeguards that have been put in place to ensure their safety, efficacy, and quality. It sets out the progress and challenges in meeting the immunization-related global goals. It discusses both the cost of scaling up immunization coverage to meet these goals, and efforts to ensure that the achievements are sustainable in the long term. Finally, it looks beyond 2015 to likely changes in the immunization landscape. Part 2 describes over 20 vaccine-preventable diseases and reviews progress since 2000 in efforts to protect populations against these diseases through the use of vaccines.--Publisher's description.

Cholera; Diptheria; Haemophilus influenzae type b; Hepatitis A; Hepatitis B; Human papillomavirus; Influenza; Japanese encephalitis; Measles; Meningococcal disease; Mumps; Pertussis; Pneumococcal disease; Polio; Rabies;Rotavirus; Rubella; Tetanus; Tuberculosis; Varicella and herpes zoster; Yellow fever.