Correspondence, diaries (1914-1953), articles, speeches, lectures, clippings, scrapbooks, printed matter, photographs, memorabilia, and organizational records relating to Sanger's extensive activities on behalf of birth control in the U.S. and throughout the world. Includes material relating to many national and international congresses and conferences organized by Sanger, her campaign to enlist public opinion and congressional support for federal legislation on birth control, and material relating to her interest and activity in socialist politics and liberal reform groups. Includes records of various birth control groups with which she was associated, such as American Birth Control League, Birth Control Clinical Research Bureau, National Committee on Federal Legislation for Birth Control, Birth Control Federation of America, Margaret Sanger Research Bureau, and Planned Parenthood Federation of America.

Correspondents include Ruth Manierre Delafield, Françoise Rousel Delisle, Hugh De Sélincourt, Havelock Ellis, James Waldo Fawcett, Richard Figdor, Clarence James Gamble, Emma Goldman, Julian Huxley, Shizué Kato, Anne Kennedy, Mabel Dodge Luhan, Kitty Marion, Katherine Dexter McCormick, Ruth P. Pinchot, Florence Rose, J. Rutgers, Marie Charlotte Carmichael Stopes, Rabindranath Tagore, H. G. Wells, and the Watumull Foundation.