Founded by the Greeks around 1000 BC, Ephesus had a long and eventful history as Greek and Hellenistic city cops. However, it was under the rule of Rome, aided by various emperors, when it became one of the most beautiful cities of the Empire, the jewel of the provincial capitals. The Ephesians acquired new habits, such as bathrooms and holding gladiatorial combat, but also their culture proudly preserved Greek culture (the philosopher Heraclitus was always his most illustrious citizen) and promoted the establishment of schools of rhetoric and medicine. The history of Ephesus would change with the arrival of Christianity. While it continued to be an important religious center, over time the city ended up being devastated by earthquakes and wars, and finally abandoned. In Ephesus, Greece and Rome synthesis provides a complete analysis of one of the most fascinating sites of antiquity, whose historical paradigm makes the rise and fall of the classical world.