12 year-old Meggie lives with her father, Mortimer, a bookbinder. Mo never reads stories aloud to Meggie because he has a special gift: when he reads a book aloud, the characters come out of the book and into the real world.

One night, when Meggie was a small child, Mortimer was reading aloud from a book named Inkheart when an evil villain named Capricorn, his aide Basta, and a fire-eater named Dustfinger escape from the book and into their living room. At the same time, Mo's wife Resa gets trapped within the book.

Twelve years later, Capricorn is on a hunt to find and destroy all copies of Inkheart and use Mo's abilities to gain more power for himself in the real world. Meggie discovers her father's secret and, along with the help of Dustfinger and Meggie's eccentric aunt Elinor, fights to free her father and destroy Capricorn.