MARC Record from harvard_bibliographic_metadata

LEADER: 03851nam a2200397 a 4500
001 009501936-7
005 20041124140949.0
008 031209s2004 njua b 001 0 eng
010 $a 2003026920
020 $a047144460X (cloth : alk. paper)
035 0 $aocm53937807
040 $aDNLM/DLC$cDLC$dDLC
042 $apcc
050 00 $aRC267$b.M68 2004
060 10 $aQZ 200$bM932 2004
082 00 $a616.99/4027$222
245 00 $aMouse models of human cancer /$cedited by Eric C. Holland.
260 $aHoboken, N.J. :$bWiley-Liss,$cc2004.
300 $axi, 474 p., [8] p. of plates :$bill. (some col.) ;$c29 cm.
504 $aIncludes bibliographical references and index.
505 0 $aApproaches to handling, breeding, strain preservation, genotyping, and drug administration for mouse models of cancer / Dawnalyn Boggess ... [et al.] -- Pathology of mouse models of cancer / Robert D. Cardiff -- Intercurrent infections in genetically engineered mice / Stephen W. Barthold -- Germ line modification strategies / Silvia Grisendi and Pier Paolo Pandolfi -- Somatic cell gene transfer / Lene Uhrbom and Eric C. Holland -- Lung cancer / Jonathan M. Kurie ... [et al.] -- Mammary gland cancer / Dalit Barkan ... [et al.] -- Prostate cancer / Katharine Ellwood-Yen and Charles Sawyers -- Skin cancer / Marcus Bosenberg.
505 8 $aOvarian cancer / Sandra Orsulic -- Peripheral nervous system tumors / David H. Gutmann ... [et al.] -- Central nervous system tumors / Andrew B. Lassman and Eric C. Holland -- Myeloid malignancies / Scott C. Kogan -- Lymphoid malignancies / Michael Teitell and Pier Paolo Pandolfi -- Genetic modifiers / David W. Threadgill ... [et al.] -- Modeling blood vessel formation in the mouse / Robert Benezra, Shahin Rafii, and David Lyden -- Metastasis / Dawn S. Chandler and Guillermina Lozano -- Immunologic study of tumors in mouse models / Taha Merghoub and Alan N. Houghton -- Micro-computed tomography of mouse cancer models / Jamey P. Weichert.
505 8 $aMagnetic resonance imaging in mouse cancer models / Manickam Muruganandham and Jason A. Koutcher -- Bioluminescent imaging of mouse cancer models / Christopher H. Contag -- Use of magnetic resonance imaging (MRI) for evaluation treatment response / Brian D. Ross ... [et al.] -- Physiologically based pharmacokinetic and pharmacodynamic modeling / Raymond S. H. Yang ... [et al.] -- Trial design and biostatistics / Michael F.W. Festing -- Cancer drug development in the modern era / William R. Sellers and Alex Matter -- Pre-clinical trials in mouse cancer models / Brian Weiss and Kevin Shannon.
520 $aMice have become the species of choice for modeling the complex interactions between tumor cells and the host environment. Mouse genetics are easily manipulated, and a growing array of technology exists for this purpose. Mouse models allow investigators to better understand causal relationships between specific genetic alterations and tumors, utilize new imaging techniques, and test novel therapies. Recent developments along these lines show great promise for the development of new anti-cancer treatments. This text provides researchers and students with a complete resource on the subject, systematically presenting the principles, methodologies, applications, and challenges associated with this exciting field.
650 0 $aCancer$xAnimal models.
650 0 $aMice$xDiseases$xPathophysiology.
650 12 $aNeoplasms$xphysiopathology.
650 12 $aDisease Models, Animal.
650 22 $aAnimals, Genetically Modified.
650 22 $aAntineoplastic Agents.
650 22 $aDrug Evaluation, Preclinical.
650 22 $aMice, Inbred Strains.
700 1 $aHolland, Eric C.
776 08 $iOnline version:$tMouse models of human cancer.$dHoboken, N.J. : Wiley-Liss, c2004$w(OCoLC)607661065
988 $a20040922
906 $0OCLC