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LEADER: 05594pam a22005054a 4500
001 010295808-4
005 20080109103843.0
008 050811s2006 sz a b 001 0 eng
010 $a 2005023395
016 7 $a101254922$2DNLM
020 $a3805579608 (hard cover : alk. paper)
020 $a9783805579605 (hard cover : alk. paper)
035 0 $aocm61334479
040 $aDNLM/DLC$cDLC$dNLM$dBAKER$dOHX$dC#P$dMUQ$dNLGGC$dBTCTA$dYDXCP$dHMS
042 $apcc
050 00 $aRC858.C95$bC972 2006
060 00 $aW1$bPR681DM v.34 2006
060 10 $aWI 820$bC9978 2006
082 00 $a616.3/72$222
245 00 $aCystic fibrosis in the 21st century /$cvolume editors, Andrew Bush ... [et al.].
246 3 $aCystic fibrosis in the twenty-first century
260 $aBasel ;$aNew York :$bKarger,$cc2006.
300 $aix, 329 p. :$bill. (some col.) ;$c29 cm.
440 0 $aProgress in respiratory research,$x1422-2140 ;$vv. 34
504 $aIncludes bibliographical references and indexes.
505 0 $aThe CFTR gene: structure, mutations and specific therapeutic approaches / Nissim-Rafinia, M., Linde, L., Kerem, B. -- Exquisite and multilevel regulation of CFTR expression / Trezise, A.E.O. -- Intracellular processing of CFTR / Barriere, H., Lukacs, G.L. -- Structure of the cystic fibrosis transmembrane conductance regulator / Stratford, F.L.L., Bear, C.E. -- Function of CFTR protein: ion transport / Chen, J.-H. ... [et al.] -- Cystic fibrosis. Function of CFTR Protein: regulatory functions / Coakley, R.D., Stutts, M.J. -- Function of CFTR protein: developmental role / Gill, D., Larson, J.E. -- Genotype-phenotype correlations in cystic fibrosis / Dorfman, R., Zielenski, J.
505 8 $aDiagnosis of cystic fibrosis, CFTR-related disease and screening / Karczeski, B.A., Cutting, G.R. -- CF modifier genes / Griesenbach, U., Alton, E.W.F.W., Davies, J.C. -- Animal models / Dorin, J.R -- In vitro/ex vivo fluorescence assays of CFTR chloride channel function / Verkman, A.S., Galietta, L.J.V. -- In vivo measurement of airway potential difference to assess CFTR function in man / Middleton, P., Alton, E.W.F.W. -- Arrays and proteomics / Ogilvie, V.C., MacGregor, G. -- Pathogenesis of pulmonary disease in cystic fibrosis / Mall, M., Boucher, R.C. -- Infection versus inflammation / Ziady, A.G., Davis, P.B.
505 8 $aPseudomonas aeruginosa: clinical research / Armstrong, D. -- Pseudomonas aeruginosa: basic research / Scott, F.W., Pitt, T.L. -- Other gram-negative organisms: Burkholderia cepacia complex and Stenotrophomonas maltophilia / Govan, J.R.W. -- Staphylococcus aureus and MRSA / Conway, S., Denton, M. -- Nontuberculous mycobacterial lung disease in patients with cystic fibrosis / Griffith, D.E -- Respiratory fungal infections and allergic bronchopulmonary aspergillosis / Que, C., Geddes, D. -- Advanced disease management and advances in transplant medicine / Carby, M.R., Hodson, M.E. -- Current and novel antimicrobial approaches / Davies, J.C.
505 8 $aAnti-inflammatory agents: a clinical perspective / Hilliard, T.N., Balfour-Lynn, I.M. -- Recent advances in infant and pre-school lung function / Ranganathan, S. -- Recent advances in imaging / Oikonomou, A., Hansell, D.M. -- New pharmacological approaches for treatment of cystic fibrosis / Rubenstein, R.C. -- Gene and stem cell therapy / Boyd, A.C. -- Gut disease: clinical manifestations, pathophysiology, current and new treatments / Taylor, C.J., Hardcastle, J. -- Pancreatic involvement: clinical manifestations, pathophysiology and new treatments / Lindley, K.J. -- Cystic fibrosis: liver disease / Westaby, D.
505 8 $aFertility, contraception, incontinence and pregnancy / Thorpe-Beeston, J.G. -- Arthritis, vasculitis and bone disease / Elkin, S. -- Diabetes in cystic fibrosis / Bridges, N., Spowart, K. -- Challenges for nurses / Madge, S. -- Dietetics / Wolfe, S., Morton, A. -- Physiotherapy / Pryor, J.A. ... [et al.] -- Psychological interventions / Bryon, M. -- The future / Bush, A. ... [et al.].
520 $aCystic fibrosis used to be thought of as a respiratory and digestive disease, with a uniformly and rapidly fatal outcome. The spectrum of the disease has broadened into the mild atypical case, presenting in middle age, with the potential for complications in virtually every system of the body. In the past few years there has been an explosion of knowledge of the basic science of the defect. Although there are many "Recent Advances" texts, previous books have been selective in their choice of topics. This book is the first to cover the entire field of this complex disease, and encompasses the rapidly moving topics of the basic molecular and cellular biology as well as the recent multi-system, multi-disciplinary advances in the clinical care of patients. The authors have been charged with writing only about new developments and not to rehash old literature. The bulk of the references is therefore less than five years old.
650 0 $aCystic fibrosis.
650 0 $aCystic fibrosis$xGenetic aspects.
650 12 $aCystic Fibrosis$xcomplications.
650 12 $aCystic Fibrosis$xgenetics.
650 22 $aCystic Fibrosis Transmembrane Conductance Regulator$xgenetics.
650 22 $aCystic Fibrosis Transmembrane Conductance Regulator$xmetabolism.
650 22 $aLung$xphysiopathology.
650 6 $aMucoviscidose.
650 6 $aMucoviscidose$xAspect génétique.
650 17 $aKystische fibrose.$2gtt
700 1 $aBush, Andrew,$d1954 April 24-
700 1 $aBush, Andrew,$d1954 Apr. 24-
988 $a20070429
906 $0OCLC