MARC Record from harvard_bibliographic_metadata

LEADER: 03490cam a2200457 a 45e0
001 011370577-8
005 20090113203627.0
008 080124s2004 gw af b 001 0 eng
010 $a 2004303455
015 $aGBA442763
016 7 $a012930164$2Uk
016 7 $a97039568X$2GyFmDB
020 $a9783527309801 (alk. paper)
020 $a3527309802 (alk. paper)
040 $aUKM$cUKM$dC#P$dDLC$dCUX$dOHX$dWJ7
041 0 $aeng
042 $anlmcopyc
050 4 $aQH597$b.C46 2004
060 00 $a2005 E-592
060 10 $aQU 350$bC397 2004
072 7 $aQP$2lcco
082 04 $a571.65$222
245 00 $aCentrosomes in development and disease /$cedited by Erich A. Nigg.
260 $aWeinheim :$bWiley-VCH,$cc2004.
300 $axlii, 431 p., 20 p. of plates :$bill. (some col.) ;$c25 cm.
504 $aIncludes bibliographical references and index.
505 0 $aEarly studies on centrioles and centrosomes -- Tubulin superfamily -- Microtubule nucleation -- The budding yeast spindle pole body: a centrosome analog -- Dissection of basal body and centriole function in the unicellular green alga chlamydomonas reinhardtii -- The centrosome in evolution -- A proteomic approach to the inventory of the human centrosome -- The role of the centrosome in cell cycle progression -- Centrosome duplication and its regulation in the higher animal cell -- A synergy of technologies: using green fluorescent protein tagging and laser microsurgery to study centrosome function and duplication in vertebrates.
505 8 $aCentrosome regulation in response to environmental and genotoxic stress -- The C. elegans centrosome during early embryonic development -- Centrosomes in a developing organism: lessons from drosophila -- Centrosome inheritance during human fertilization and "therapeutic" cloning: reproductive and developmental diseases and disorders caused by centrosome dysfunction -- Microtubule organizing centers in polarized epithelial cells -- Centrosome anomalies in cancer: from early observations to animal models -- Radiation therapy and centrosome anomalies in pancreatic cancer -- Radiation therapy and centrosome anomalies in pancreatic cancer.
505 8 $aHuman papillomavirus infection and centrosome anomalies in cervical cancer -- Manipulation of centrosomes and the microtubule cytoskeleton during infection by intracellular pathogens -- Basal bodies and microtubule organization in pathogenic protozoa.
530 $aAlso available in an electronic version.
538 $aMode of access: World Wide Web.
520 $aDiscovered over a century ago, the centrosome is the major microtubule organizing center of the animal cell. It is a tiny organelle of surprising structural complexity. Over the last few years our understanding of the structure and composition of centrosomes has greatly advanced, and the demonstration of frequent centrosome anomalies in most common human tumors has sparked additional interest in the role of this organelle in a broader scientific community. The centrosome controls the number and distribution of microtubules--a major element of the cell cytoskeleton--and hence influences many impo.
655 0 $aElectronic books.
650 22 $aNeoplasms.
650 22 $aCell Division$xphysiology.
650 12 $aCentrosome$xphysiology.
655 7 $aComputer network resources.$2local
700 1 $aNigg, Erich A.
740 0 $aCentrosomes in development and disease (Online)$5med
988 $a20080124
906 $0OCLC