MARC Record from harvard_bibliographic_metadata

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041 0 $aeng
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050 4 $aQP751$b.F38 2007
060 00 $aW1$bNO9285 v.286 2007
060 10 $aQU 90$bF2534 2007
082 04 $a612.397$222
245 00 $aFatty acids and lipotoxicity in obesity and diabetes.
260 $aChichester, UK ;$aHoboken, NJ :$bJohn Wiley,$c2007.
300 $aix, 211 p. :$bill.
440 0 $aNovartis Foundation symposium ;$v286
500 $aSymposium on fatty acids and lipotoxicity in obesity and diabetes, held at Tsinghua University, Beijing, China, 17-19 Oct. 2006.
500 $aEditors: Gregory Bock and Jamie Goode.
504 $aIncludes bibliographical references and indexes.
505 0 $aTranscriptional control of energy homeostasis through the PGC1 coactivators / B.M. Spiegelman -- Human obesity and insulin resistance: lessons from experiments of nature / S. O'Rahilly -- Lipid-induced metabolic dysfunction in skeletal muscle / D.M. Muoio and T.R. Koves -- Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes / A.D. Attie ... [et al.] -- The role of lipin 1 in adipogenesis and lipid metabolism / K. Reue -- The role of the AMP-activated protein kinase in the regulation of energy homeostasis / D. Carling -- Endoplasmic reticulum stress and inflammation in obesity and type 2 diabetes / G.S. Hotamisligil -- The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis / I. Tabas ... [et al.] -- Fatty acid transport in adipocytes and the development of insulin resistance / S. Lobo and D.A. Bernlohr -- Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking / P.N. Black and C.C. DiRusso -- Lipid storage and mobilization pathways in yeast / G. Daum ... [et al.] -- Cide proteins and the development of obesity / J.Z. Li and P. Li -- Adiponectin and adiponectin receptors in obesity-linked insulin resistance / T. Kadowaki ... [et al.] -- Anti-inflammatory and antidiabetic roles of PPARgamma / G. Pascual ... [et al.].
520 $aThe potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic 'B' cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires coordinated regulation between the liver, adipose tissue and skeletal muscle. This book deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue biology, and 'B' cell function and insulin resistance. Chapters deal with the molecular genetics and molecular physiology of energy homeostasis.
650 22 $aObesity.
650 22 $aAdipose Tissue.
650 22 $aLipid Metabolism.
650 12 $aFatty Acids.
655 2 $aCongresses
650 12 $aFatty Acids$vCongresses.
650 22 $aAdipose Tissue$vCongresses.
650 22 $aLipid Metabolism$vCongresses.
650 22 $aObesity$vCongresses.
650 22 $aDiabetes Mellitus
650 0 $aLipids$xMetabolism$vCongresses.
650 0 $aFatty acids$vCongresses.
650 0 $aAdipose tissues$vCongresses.
650 0 $aObesity$vCongresses.
650 0 $aDiabetes$vCongresses.
655 7 $aConference proceedings.$2fast
700 1 $aBock, Gregory.
700 1 $aGoode, Jamie.
710 2 $aNovartis Foundation.
710 2 $aQing hua da xue (Beijing, China)
776 08 $iOnline version:$tFatty acids and lipotoxicity in obesity and diabetes.$dChichester, UK ; Hoboken, NJ : John Wiley, 2007$w(OCoLC)606382021
776 08 $iOnline version:$tFatty acids and lipotoxicity in obesity and diabetes.$dChichester, UK ; Hoboken, NJ : John Wiley, 2007$w(OCoLC)608607678
988 $a20080206
906 $0OCLC