MARC Record from harvard_bibliographic_metadata

LEADER: 02739cam a2200313Ia 4500
001 011385070-0
005 20080723161446.0
008 070315s2007 ne a b 001 0 eng d
020 $a9781402060861
020 $a1402060866
035 0 $aocn144228494
040 $aBTCTA$cBTCTA$dBAKER$dYDXCP$dOHX$dMMU$dEMU
050 4 $aRC271.I45$bG46 2007
245 00 $aGeneral principles of tumor immunotherapy :$bbasic and clinical applications of tumor immunology /$cedited by Howard L. Kaufman and Jedd D. Wolchok.
260 $aDordrecht :$bSpringer,$cc2007.
300 $axii, 503 p. :$bill. ;$c25 cm.
504 $aIncludes bibliographical references and index.
505 0 $aGeneral principles of tumor immunology -- A perspective on cancer immunology and immunotherapy -- Tumor antigens -- T cells and antigen recognition -- The role of natural killer T cells in tumor immunity -- Immunomodulatory molecules of the immune system -- HLA class I antigen abnormalities in tumors -- The local tumor microenvironment -- Tumor vaccines -- Peptide and protein vaccines for cancer -- DNA vaccines against cancer -- Recombinant viral and bacterial vaccines -- Dendritic cell vaccines -- Whole cell vaccines -- Carbohydrate vaccines against cancer -- Passive immunotherapy approaches -- Monoclonal antibody therapy of cancer -- Adoptive cellular therapy for the treatment of cancer -- Checkpoint blockade and combinatorial immunotherapies -- Clinical tumor immunotherapy -- General approaches to measuring immune responses -- Interferon therapy -- High dose interleuken-2 therapy -- Monoclonal antibodies in cancer therapy -- Unmasking tumor cell immunogenicity by chemotherapy: implications for therapy.
520 $aThis book brings together the world's leading authorities on tumor immunology. It describes the basic immunology principles that form the foundation of understanding how the immune system recognizes and rejects tumor cells. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated through both experimental clinical trials and review of current standard of care therapeutic agents. The book provides a comprehensive overview of the field, demonstrates how advances in basic immunology can and are being applied to cancer, and describes the current status of approved immunotherapy regimens.
650 0 $aCancer$xImmunotherapy.
650 0 $aCancer vaccines.
650 12 $aNeoplasms$xtherapy.
650 22 $aNeoplasms$ximmunology.
650 22 $aImmunotherapy.
650 22 $aCancer Vaccines$xtherapeutic use.
700 1 $aKaufman, Howard L.
700 1 $aWolchok, Jedd D.
988 $a20080213
906 $0OCLC