MARC Record from harvard_bibliographic_metadata

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008 090219s2009 nyu b 001 0 eng
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040 $aDNLM$cDNLM
041 0 $aeng
042 $apcc
050 00 $aQR185.8.T84$bT44 2009
060 10 $aW1$bAD559 v.647 2009
060 10 $aQW 568$bT3985 2009
245 00 $aTherapeutic targets of the TNF superfamily /$cedited by Iqbal S. Grewal.
260 $aNew York :$bSpringer Science+Business Media ;$aAustin, Tex. :$bLandes Bioscience,$cc2009.
490 1 $aAdvances in experimental medicine and biology ;$vv. 647
504 $aIncludes bibliographical references and index.
505 0 $aOverview of TNF superfamily : a chest full of potential therapeutic targets / Iqbal S. Grewal -- Therapeutic interventions targeting CD40l (CD154) and CD40 : the opportunities and challenges / Che-Leung Law and Iqbal S. Grewal -- Targeting TNF for treatment of cancer and autoimmunity / Gautam Sethi ... [et al.] -- Targeting of BAFF and APRIL for autoimmunity and oncology / Maureen C. Ryan and Iqbal S. Grewal -- The role of FASL and FAS in health and disease / Martin Ehrenschwender and Harald Wajant -- OX40 (CD134) and OX401 / Michael J. Gough and Andrew D. Weinberg -- Targeting CD70 for human therapeutic use / Tamar Boursalian ... [et al.] -- 4-1BB as a therapeutic target for human disease / Seung-Woo Lee and Michael Croft -- Rank(l) as a key target for controlling bone loss / Andreas Leibbrandt and Josef M. Penninger -- Targeting the light-HVEM pathway / Carl F. Ware --
505 0 $aGITR : a modulator of immune response and inflammation / Giuseppe Nocentini and Carlo Riccardi -- Targeting CD30/CD30l in oncology and autoimmune and inflammatory diseases / Ezogelin Oflazoglu, Iqbal S. Grewal, and Hans Peter Gerber -- Tumor necrosis factor receptor superfamily member 21 : TNFR-related death receptor-6, DR6 / Robert Benschop, Tao Wei, and Songqing Na -- TRAIL and other TRAIL receptor agonists as novel cancer therapeutics / Christina Falschlehner ... [et al.] -- Therapeutic potential of VEGI/TL1A -- In autoimmunity and cancer / Gautam Sethi, Bokyung Sung, and Bharat B. Aggarwal.
520 $aThis volume presents the state-of-the art account on the role of TNF superfamily members in the pathogenesis and their use in current intervention of cancers and autoimmune disease. This text will be highly valuable for investigators to understand the disease processes regulated by TNF superfamily members and to develop effective therapeutics. A view into the future, inspired by the comprehensive work presented in this volume, predicts that researchers studying TNF superfamily members will continue to make rapid progress in identifying relevant components to the disease process and new therapeutic strategies to target many human diseases including cancers, autoimmune disease and others.
650 22 $aReceptors, Tumor Necrosis Factor$xtherapeutic use.
650 22 $aNeoplasms$xdrug therapy.
650 22 $aInflammation$xdrug therapy.
650 22 $aAutoimmune Diseases$xdrug therapy.
650 12 $aTumor Necrosis Factors$xtherapeutic use.
650 0 $aTumor necrosis factor.
650 0 $aTumor necrosis factor$xAgonists$xTherapeutic use.
700 1 $aGrewal, Iqbal S.
830 0 $aAdvances in experimental medicine and biology ;$vv. 647.
988 $a20090219
906 $0OCLC