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Record ID harvard_bibliographic_metadata/ab.bib.12.20150123.full.mrc:309884482:2468
Source harvard_bibliographic_metadata
Download Link /show-records/harvard_bibliographic_metadata/ab.bib.12.20150123.full.mrc:309884482:2468?format=raw

LEADER: 02468cam a22003974a 4500
001 012334779-3
005 20091125154648.0
008 080721s2009 nyuabf b 001 0 eng
010 $a 2008032334
015 $aGBA936309$2bnb
016 7 $a101479415$2DNLM
016 7 $a015109061$2Uk
020 $a9780521875196 (hardback)
020 $a0521875196 (hardback)
035 0 $aocn236052716
040 $aDNLM/DLC$cDLC$dYDX$dNLM$dBTCTA$dYDXCP$dUKM$dCDX$dDLC
042 $apcc
050 00 $aRC641.7.H35$bD575 2009
060 00 $a2009 J-610
060 10 $aWH 190$bD612 2009
082 00 $a616.1/51$222
245 00 $aDisorders of hemoglobin :$bgenetics, pathophysiology, and clinical management /$cedited by Martin H. Steinberg ... [et al.].
250 $a2nd ed.
260 $aNew York :$bCambridge University Press,$c2009.
300 $axx, 826 p., [36] p. of plates :$bill. (some col.), maps ;$c29 cm.
490 1 $aCambridge medicine
504 $aIncludes bibliographical references and index.
520 $aThis book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with a and B thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy.
650 0 $aHemoglobinopathy.
650 12 $aHemoglobinopathies$xgenetics.
650 22 $aHemoglobinopathies$xphysiopathology.
650 22 $aHemoglobinopathies$xtherapy.
700 1 $aSteinberg, Martin H.
830 0 $aCambridge medicine.
988 $a20100430
906 $0OCLC