MARC Record from harvard_bibliographic_metadata

LEADER: 03865cam a2200553 i 4500
001 013898094-2
005 20140314190904.0
006 m o d
008 131206s2014 gw o 000 0 eng d
020 $a9783642405914 (electronic bk.)
020 $a3642405916 (electronic bk.)
020 $z9783642405907
024 7 $a10.1007/978-3-642-40591-4$2doi
035 0 $aocn864753031
040 $aGW5XE$beng$erda$epn$cGW5XE$dZMC
050 4 $aQR201.L44
060 4 $aWC 200
072 7 $aMMFM$2bicssc
072 7 $aMED052000$2bisacsh
082 04 $a616.2/4101$223
245 00 $aMolecular mechanisms in Legionella pathogenesis /$cedited by Hubert Hilbi.
264 1 $aHeidelberg :$bSpringer,$c[2014]
264 4 $c©2014
300 $ax, 295 pages :$billustrations ;$c24 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
490 1 $aCurrent topics in microbiology and immunology,$x0070-217X ;$vvolume 376
504 $aIncludes bibliographical references and index.
505 00 $tFrom Amoeba to Macrophages: Exploring the Molecular Mechanisms of Legionella pneumophila Infection in Both Hosts /$rPedro Escoll and Monica Rolando --$tThe Legionella pneumophila Two-Component Regulatory Systems that Participate in the Regulation of Icm/Dot Effectors /$rGil Segal --$tFacets of Small RNA-Mediated Regulation in Legionella pneumophila /$rHana Trigui, Nilmini Mendis and Laam Li --$tType II Secretion and Legionella Virulence /$rNicholas P. Cianciotto --$tEffector Translocation by the Legionella Dot/Icm Type IV Secretion System /$rJiazhang Qiu and Zhao-Qing Luo --$tModulation of Small GTPases by Legionella /$rRoger S. Goody and Aymelt Itzen --$tHost Lipidation: A Mechanism for Spatial Regulation of Legionella Effectors /$rStanimir S. Ivanov and Craig Roy --$tPhosphoinositide Lipids and the Legionella Pathogen Vacuole /$rIna Haneburger and Hubert Hilbi --$tLegionella Phospholipases Implicated in Virulence /$rKatja Kuhle and Antje Flieger --$tCytotoxic Glucosyltransferases of Legionella pneumophila /$rYury Belyi, Thomas Jank and Klaus Aktories --$tModulation of the Ubiquitination Machinery by Legionella /$rAndree Hubber, Tomoko Kubori and Hiroki Nagai --$tHost Signal Transduction and Protein Kinases Implicated in Legionella Infection /$rAndrew D. Hempstead and Ralph R. Isberg --$tMouse Models of Legionnaires' Disease /$rAndrew S. Brown and Ian R. van Driel.
520 $aLegionnaires' disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a state-of-the-art overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.
650 20 $aBacteriology.
650 20 $aImmunology.
650 20 $aCommunicable diseases.
650 20 $aInfection.
650 20 $aMedical microbiology.
650 12 $aLegionnaires' Disease.
650 12 $aLegionella pneumophila$xpathogenicity.
650 0 $aLegionella pneumophila.
650 0 $aLegionnaires' disease$xMolecular aspects.
650 14 $aBiomedicine.
650 24 $aMolecular Medicine.
650 2 $aLegionella pneumophila.
650 2 $aPathology, Molecular.
700 1 $aHilbi, Hubert,$eeditor of compilation.
700 1 $aHilbi, Hubert,$eeditor.
830 0 $aCurrent topics in microbiology and immunology ;$v376.
988 $a20140108
906 $0OCLC