MARC Record from harvard_bibliographic_metadata

LEADER: 04013cam a2200589 a 4500
001 013220475-4
005 20120608190931.0
006 m d
008 110624s2011 caua ob 000 0 eng
016 7 $a101563674$2DNLM
020 $a9781615041787 (electronic bk.)
020 $a1615041788 (electronic bk.)
020 $z9781615041770 (pbk.)
020 $z161504177X (pbk.)
024 7 $a10.4199/C00029ED1V01Y201103ISP017$2doi
035 0 $aocn712606903
040 $aNLM$beng$cNLM$dORE$dOHS$dUBY$dVAM$dCUS$dCGU$dCOO$dN$T$dEBLCP$dE7B
042 $anlmcopyc
050 4 $aQP99.3.O9$bP58 2011eb
060 00 $a2011 I-552
060 10 $aQV 312
072 7 $aNAT$x019000$2bisacsh
072 7 $aSCI$x070030$2bisacsh
082 04 $a599.012$222
100 1 $aPittman, Roland N.
245 10 $aRegulation of tissue oxygenation$h[electronic resource] /$cRoland N. Pittman.
260 $aSan Rafael, Calif. :$bMorgan & Claypool Life Sciences,$cc2011.
300 $a1 online resource (ix, 89 p.) :$bill. (some col.)
490 1 $aIntegrated systems physiology, from molecule to function to disease ;$v#17
500 $aTitle from Web page (viewed on April 13, 2011).
504 $aIncludes bibliographical references (p. 81-88).
520 3 $aThis presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 in their vicinity falls to a critical level of about 1 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2. In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
505 0 $aIntroduction -- The Circulatory System and Oxygen Transport -- The Respiratory System and Oxygen Transport -- Oxygen Transport -- Chemical Regulation of Respiration -- Tissue Gas Transport -- Oxygen Transport in Normal and Pathological Situations: Defects and Compensations -- Matching Oxygen Supply to Oxygen Demand -- Exercise and Hemorrhage -- Measurement of Oxygen -- Summary.
650 7 $aSCIENCE / Life Sciences / Zoology / Mammals.$2bisacsh
650 7 $aNATURE / Animals / Mammals.$2bisacsh
650 12 $aBiological Transport.
650 12 $aOxygen$xphysiology.
650 22 $aBlood Physiological Processes.
650 22 $aOxygen$xmetabolism.
650 22 $aRespiratory Physiological Processes.
650 0 $aOxygen$xPhysiological transport.
650 0 $aOxygen in the body.
653 $aCardiovascular system
653 $aRespiratory system
653 $aBlood
653 $aMicrocirculation
653 $aOxygen transport
655 4 $aElectronic books.
830 0 $aColloquium series on integrated systems physiology ;$v#17.
988 $a20120529
049 $aHMSS
906 $0OCLC