MARC Record from harvard_bibliographic_metadata

LEADER: 03546cam a2200505 a 4500
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008 940609s1994 enka b 001 0 eng
010 $a 94026309
016 7 $a9505770$2DNLM
020 $a0521449502 (pbk.)
020 $a9780521449502 (pbk.)
020 $a9780511608438 (ebook)
020 $a0521445000
020 $a9780521445009
035 0 $aocm30701944
040 $aDLC$beng$cDLC$dMMU$dAGL$dNLM$dBAKER$dBTCTA$dYDXCP$dB9K$dCOCUF$dDEBBG$dOCLCQ$dZWZ
050 00 $aQP601.3$b.S38 1994
060 00 $a1995 D-030
060 10 $aQU 135$bS388e 1994
070 0 $aQP601.3.S38$b1994
072 0 $aX500
082 00 $a574.19/25$220
084 $aCHE 827f$2stub
084 $aWD 5050$2rvk
100 1 $aSchulz, Arthur R.
245 10 $aEnzyme kinetics :$bfrom diastase to multi-enzyme systems /$cArthur R. Schulz.
260 $aCambridge ;$aNew York :$bCambridge University Press,$c1994.
300 $ax, 246 p. :$bill. ;$c23 cm.
504 $aIncludes bibliographical references and indexes.
505 0 $apt. 1. Basic steady state enzyme kinetics. 1. Derivation of a rate equation. 2. A closer look at the basic assumptions. 3. Enzyme inhibition. 4. Reversible enzyme-catalyzed reactions -- pt. 2. Enzyme reaction sequence. 5. Multi-reactant enzymic reactions. 6. Analysis of multi-reactant enzyme kinetics. 7. Prediction of reaction sequence. 8. Enzyme-catalyzed isotopic exchange. 9. Kinetic isotope effect on steady state parameters. 10. The effect of pH on enzyme kinetics -- pt. 3. Non-hyperbolic enzyme kinetics. 11. The causes of non-hyperbolic enzyme kinetics. 12. Analysis of non-hyperbolic enzyme kinetics. 13. The effect of subunit interactions on enzyme kinetics -- pt. 4. Control of multi-enzyme systems. 14. Control of linear multi-enzyme systems. 15. Control of branched multi-enzyme systems. 16. Biochemical systems theory -- pt. 5. Solutions to problems.
520 $aThis textbook for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady state enzyme kinetics from the basic principles inherent in the Henri equation to the expressions which describe the control of multi-enzyme pathways.
520 8 $aSteady state kinetic equations are derived with the use of the connection matrix method, and an algorithm which can be implemented easily for computer-based derivation of the equations is developed. Throughout the book emphasis is placed on a proper interpretation of the kinetic behavior of multi-reactant enzymic reactions. The principles of analytical geometry and basic calculus are employed to analyze non-hyperbolic substrate saturation curves in terms of the mechanisms, including subunit interactions, which cause the deviation from hyperbolic curves. Sensitivity theory is employed to obtain expressions for flux and concentration control coefficients for multi-enzyme pathways. The algorithm developed can be incorporated into a computer-based program for derivation. Emphasis is placed on the interpretation of control coefficients in terms of metabolic control. Problems are included at the end of each chapter and their solutions are found at the end of the book.
650 0 $aEnzyme kinetics.
650 12 $aEnzymes$xmetabolism.
650 22 $aKinetics.
650 22 $aBiophysics.
650 22 $aModels, Theoretical.
650 07 $aEnzymkinetik.$2swd
650 7 $aEnzymes.$2ram
650 7 $aCinétique enzymatique.$2ram
899 $a415_565300
988 $a20120109
049 $aCLSL
906 $0DLC