MARC Record from harvard_bibliographic_metadata

LEADER: 03835cam a2200529 i 4500
001 013662834-6
005 20130627020908.0
008 121203s2013 gw a 000 0 eng d
015 $aGBB2C5700$2bnb
016 7 $a016230133$2Uk
020 $a9783642273391 (hbk.)
020 $a3642273394 (hbk.)
020 $a9783642273407 (e-book)
020 $a3642273408 (e-book)
035 0 $aocn821703422
040 $aUKMGB$beng$erda$cUKMGB$dOCLCO$dBTCTA$dYDXCP$dOHX$dSCB
050 4 $aQR1$b.E6 v.369 2013
060 4 $aWC 536$bH529 2013
072 7 $aQR$2lcco
082 04 $a616.3623$223
245 00 $aHepatitis C virus :$bfrom molecular virology to antiviral therapy /$cRalf Bartenschlager, editor ; responsible series editor, Peter Vogt.
264 1 $aBerlin ;$aNew York :$bSpringer,$c[2013].
264 4 $c©2013
300 $aviii, 346 pages :$billustrations (some color) ;$c24 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
490 1 $aCurrent topics in microbiology and immunology ;$vvolume 369
504 $aIncludes bibliographical references and index.
505 0 $aThe origin of hepatitis C virus / Peter Simmonds -- Cell culture systems for hepatitis C virus / Eike Steinmann and Thomas Pietschmann -- Animal models for hepatitis C / Eva Billerbeck ... [et al.] -- Hepatitis C virus entry / Mirjam B. Zeisel, Daniel J. Felmlee and Thomas F. Baumert -- Hepatitis C virus proteins : from structure to function / Darius Moradpour and François Penin -- Hepatitis C virus RNA translation / Michael Niepmann -- Hepatitis C virus RNA replication / Volker Lohmann -- Virion assembly and release / Brett D. Lindenbach -- Innate immune responses to hepatitis C virus / John W. Schoggins and Charles M. Rice -- Adaptive immune responses in hepatitis C virus infection / Christoph Neumann-Haefelin and Robert Thimme -- Liver injury and disease pathogenesis in chronic hepatitis C / Daisuke Yamane ... [et al.] -- Hepatitis C virus-specific directly acting antiviral drugs / Leen Delang ... [et al.] -- Treatment of chronic hepatitis C : current and future / Jean-Michal Pawlotsky.
520 $aHepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted.
650 12 $aHepatitis C.
650 0 $aHepatitis C virus.
650 12 $aHepacivirus.
650 0 $aMedicine.
650 0 $aImmunology.
650 0 $aDrug interactions.
650 0 $aMedical virology.
650 0 $aClinical medicine.
650 22 $aViral Hepatitis Vaccines$xtherapeutic use.
700 1 $aBartenschlager, Ralf.
700 1 $aBartenschlager, Ralf,$eeditor of compilation.
700 1 $aBartenschlager, Ralf,$eeditor.
830 0 $aCurrent topics in microbiology and immunology ;$v369.
830 0 $aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v369
988 $a20130418
906 $0OCLC