MARC Record from harvard_bibliographic_metadata

LEADER: 03270nam a22004455a 4500
001 013716293-6
005 20130712193733.0
008 121207s2013 xxu| s ||0| 0|eng d
020 $a9781461450702
020 $a9781461450702
020 $a9781461450696
024 7 $a10.1007/978-1-4614-5070-2$2doi
035 $a(Springer)9781461450702
040 $aSpringer
050 4 $aQR180-189.5
072 7 $aMJCM$2bicssc
072 7 $aMED044000$2bisacsh
082 04 $a616.079$223
100 1 $aFlower, Darren R.
245 10 $aImmunomic Discovery of Adjuvants and Candidate Subunit Vaccines /$cedited by Darren R. Flower, Yvonne Perrie.
260 $aNew York, NY :$bSpringer New York :$bImprint: Springer,$c2013.
300 $aX, 314 p. 51 illus., 34 illus. in color.$bdigital.
490 1 $aImmunomics Reviews:, An Official Publication of the International Immunomics Society ;$v5
505 0 $aIntroduction -- Bacterial genomes and vaccine design -- Identification of candidate vaccine antigens in silico -- Post-Genomic Antigen Discovery: Bioinformatical Approaches to Reveal Novel T-Cell Antigens of Mycobacterium Bovis -- Genome-based Computational Vaccine Discovery by Reverse Vaccinology -- Computational prediction of protein subcellular localization, genomic islands, and virulence to aid antigen discovery -- On the development of Vaccine Antigen Databases: Progress, Opportunity, and Challenge -- What have Dendritic Cells ever done for adjuvant design?  Cellular and Molecular Methods for the Rational Development of Vaccine Adjuvants -- Towards the Rational Discovery of Adjuvants -- Designing liposomes as vaccine adjuvants -- Enhancing the delivery and potency of antigens using non-ionic based vesicles -- Immune stimulating complexes (ISCOMs) and Quil-A containing particulate formulations as vaccine delivery systems -- Formulation and characterisation of PLGA microspheres as vaccine adjuvants -- Powder Vaccines for Pulmonary Delivery.
520 $aVaccine discovery is one of the most exciting and fast-moving areas of applied science. Since Edward Jenner’s work in the 18th century, vaccines have transformed health across the globe. Bringing together clinical, experimental, and computational disciplines vaccinology addresses the most pressing needs of 21st century health-care: the great infectious diseases threatening the developing world, such as HIV, Malaria, and TB; and chronic diseases, such as dementia, threatening the developed world. This volume seeks to expand the horizons of vaccine design and discovery by highlighting cutting edge work in three areas of vaccinology: the rational discovery of subunit vaccines, the identification of adjuvants, and the delivery of vaccines via state-of-the-art nanotechnology.
650 20 $aBioinformatics.
650 20 $aImmunology.
650 0 $aMedicine.
650 0 $aImmunology.
650 0 $aVaccines.
650 0 $aToxicology.
650 0 $aBioinformatics.
650 14 $aBiomedicine.
650 24 $aVaccine.
650 24 $aPharmacology/Toxicology.
700 1 $aPerrie, Yvonne.
776 08 $iPrinted edition:$z9781461450696
830 0 $aImmunomics Reviews:, An Official Publication of the International Immunomics Society ;$v5.
988 $a20130627
906 $0VEN