| Record ID | harvard_bibliographic_metadata/ab.bib.13.20150123.full.mrc:874887033:2683 |
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LEADER: 02683cam a2200493Ia 4500
001 013783945-6
005 20131004191600.0
006 m o d
008 130507s2013 ne a ob 001 0 eng d
020 $a9789400763173 (electronic bk.)
020 $a9400763174 (electronic bk.)
020 $z9789400763166
035 0 $aocn841922846
040 $aGW5XE$cGW5XE$dYDXCP$dN$T$dCOO$dMHW$dE7B$dZMC$dOHS$dVAM$dOCLCA
050 4 $aRC268.45$b.R65 2013
072 7 $aHEA$x039030$2bisacsh
072 7 $aMED$x062000$2bisacsh
082 04 $a616.99/40654$223
245 00 $aRole of capsaicin in oxidative stress and cancer$h[electronic resource] /$cSanjay K. Srivastava, editor.
260 $aDordrecht :$bSpringer,$cc2013.
300 $a1 online resource (ix, 178 p.) :$bill. (some col.)
490 1 $aDiet and cancer ;$v3
504 $aIncludes bibliographical references and index.
505 0 $aRole of Capsaicin in Cancer Prevention -- Role of Death Receptors Belonging to the TNF Family in Capsaicin-Induced Apoptosis of Tumor Cells -- Role of Capsaicin in Prostate Cancer -- Capsaicin and the Urinary Bladder -- Inhibition of Pancreatitis and Carcinogenesis by Capsaicin -- Cytochrome P450-Dependent Modification of Capsaicinoids: Pharmacological Inactivation and Bioactivation Mechanisms -- The Cancer-Suppressing and -Promoting Actions of Capsaicin -- Oxidative Stress by Capsaicin in Cancer.
520 $aThis book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival p
538 $aMode of access: World Wide Web.
650 7 $aMEDICAL / Oncology.$2bisacsh
650 7 $aHEALTH & FITNESS / Diseases / Cancer.$2bisacsh
650 2 $aCapsaicin$xphysiology.
650 2 $aNeoplasms.
650 2 $aNutritional Physiological Phenomena.
650 0 $aCancer$xNutritional aspects.
650 0 $aCapsaicin$xPhysiological effect.
653 4 $aMedicine.
653 4 $aOncology.
653 4 $aGene expression.
653 4 $aCytology.
653 4 $aBiomedicine.
653 4 $aCancer Research.
653 4 $aApoptosis.
653 4 $aPharmacology/Toxicology.
988 $a20130921
096 $aQU 90
906 $0OCLC