MARC Record from harvard_bibliographic_metadata

LEADER: 02440cam a2200361 i 4500
001 013080885-7
005 20120406191312.0
008 100804s2011 njua b 001 0 eng
010 $a 2010030999
016 7 $a101537510$2DNLM
020 $a9780471771517 (cloth)
020 $a0471771511 (cloth)
035 0 $aocn655301727
040 $aDNLM/DLC$cDLC$dYDX$dNLM$dYDXCP$dCDX$dBWX$dDLC
042 $apcc
050 00 $aQP623$b.R573 2011
060 00 $a2011 D-062
060 10 $aQU 475
082 00 $a572.8/8$222
245 00 $aRNA interference :$bapplication to drug discovery and challenges to pharmaceutical development /$cedited by Paul H. Johnson.
260 $aHoboken, N.J. :$bWiley,$cc2011.
300 $axiv, 310 p. :$bill. ;$c25 cm.
504 $aIncludes bibliographical references and index.
505 8 $a(Publisher-supplied data) RNA interference: What is it? / James A. Birchler -- Nucleic acids as regulatory molecules / Faqing Huang, CJ Yu, and Yanlin Guo -- Use of siRNA oligonucleotides to study gene function / Kristin A. Wiederholt and Adam N. Harris -- Genome scanning by RNA interference / Roderick L. Beijersbergen and Oliver C. Steinbach -- Discovery of new siRNA delivery agents / Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay -- In vivo Delivery of siRNA: challenges and strategies / Aliasger K. Salem and Mark A. Behlke -- Interferon, cytokine induction and other potential in vivo toxicities / Adam Judge, Marjorie Robbins, and Ian MacLachlan -- Application of RNA interference to viral diseases / Ralph A. Tripp and Stephen Mark Tompkins.
520 $a"RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects"--Provided by publisher.
650 22 $aDrug Discovery.
650 12 $aRNA Interference.
650 0 $aRNA.
650 0 $aSmall interfering RNA.
650 0 $aDrug development.
700 1 $aJohnson, Paul H.,$d1943-
988 $a20120130
906 $0OCLC