Record ID | harvard_bibliographic_metadata/ab.bib.14.20150123.full.mrc:152127012:4447 |
Source | harvard_bibliographic_metadata |
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001 014111860-1
005 20140808191607.0
006 m|||||o||d||||||||
008 130204s2013 gw ob 001 0 eng d
020 $a9783527651085 (electronic bk.)
020 $a352765108X (electronic bk.)
020 $a9783527651115 (electronic bk.)
020 $a352765111X (electronic bk.)
020 $z9783527330737
020 $z3527330739
020 $a9781299241206 (MyiLibrary)
020 $a1299241204 (MyiLibrary)
035 0 $aocn826637765
040 $aDG1$erda$cDG1$dEBLCP$dN$T$dMHW$dYDXCP$dCOO$dIDEBK$dE7B$dNOC$dOCLCF
050 4 $aRM301.25$b.A53 2013
072 7 $aMED$x023000$2bisacsh
072 7 $aMED$x058170$2bisacsh
072 7 $aMED$x071000$2bisacsh
072 7 $aMED$x072000$2bisacsh
082 04 $a615.1/9$223
245 00 $aAnalogue-based drug discovery III /$cedited by Ja�¹nos Fischer, C. Robin Ganellin, David P. Rotella.
246 3 $aAnalogue-based drug discovery 3
264 1 $aWeinheim :$bWiley-VCH,$cc2013.
300 $a1 online resource.
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
505 0 $aGeneral Aspects. Pioneer and Analogue Drugs / Janos Fischer, C Robin Ganellin, David P Rotella -- Competition in the Pharmaceutical Drug Development / Christian Tyrchan, Fabrizio Giordanetto -- Metabolic Stability and Analogue-Based Drug Discovery / Amit S Kalgutkar, Antonia F Stepan -- Use of Macrocycles in Drug Design Exemplified with Ulimorelin, a Potential Ghrelin Agonist for Gastrointestinal Motility Disorders / Mark L Peterson, Hamid Hoveyda, Graeme Fraser, Eric Marsault, Rene Gagnon -- Drug Classes. The Discovery of Anticancer Drugs Targeting Epigenetic Enzymes / A Ganesan -- Thienopyridyl and Direct-Acting P2Y Receptor Antagonist Antiplatelet Drugs / Joseph A Jakubowski, Atsuhiro Sugidachi -- Selective Estrogen Receptor Modulators / Amarjit Luniwal, Rachael Jetson, Paul Erhardt -- Discovery of Nonpeptide Vasopressin V2 Receptor Antagonists / Kazumi Kondo, Hidenori Ogawa -- The Development of Cysteinyl Leukotriene Receptor Antagonists / Peter R Bernstein -- Case Studies. The Discovery of Dabigatran Etexilate / Norbert Hauel, Andreas Clemens, Herbert Nar, Henning Priepke, Joanne van Ryn, Wolfgang Wienen -- The Discovery of Citalopram and Its Refinement to Escitalopram / Klaus P Bogeso, Connie Sanchez -- Tapentadol : From Morphine and Tramadol to the Discovery of Tapentadol / Helmut Buschmann -- Novel Taxanes: Cabazitaxel Case Study / Herve Bouchard, Dorothee Semiond, Marie-Laure Risse, Patricia Vrignaud -- Discovery of Boceprevir and Narlaprevir: A Case Study for Role of Structure-Based Drug Design / Srikanth Venkatraman, Andrew Prongay, George F Njoroge -- A New-Generation Uric Acid Production Inhibitor: Febuxostat / Ken Okamoto, Shiro Kondo, Takeshi Nishino.
504 $aIncludes bibliographical references and index.
588 $aDescription based on title page from PDF version; (Wiley Online Library; viewed on Feb. 4, 2013).
520 $aMost drugs are analogue drugs. There are no general rules how a new drug can be discovered, nevertheless, there are some observations which help to find a new drug, and also an individual story of a drug discovery can initiate and help new discoveries. Volume III is a continuation of the successful book series with new examples of established and recently introduced drugs. The major part of the book is written by key inventors either as a case study or a study of an analogue class. With its wide range across a variety of therapeutic fields and chemical classes, this is of interest to virtu
538 $aMode of access: World Wide Web.
650 7 $aMEDICAL / Pharmacy.$2bisacsh
650 7 $aMEDICAL / Pharmacology.$2bisacsh
650 7 $aMEDICAL / Nursing / Pharmacology.$2bisacsh
650 7 $aMEDICAL / Drug Guides.$2bisacsh
650 0 $aDrug development.
650 12 $aPharmaceutical Preparations$xchemical synthesis.
650 22 $aDrug Design.
650 22 $aModels, Molecular.
650 7 $aDrug development.$2fast$0(OCoLC)fst00898670
700 1 $aFischer, Ja�¹nos.
700 1 $aGanellin, C. R.$q(C. Robin)
700 1 $aRotella, David P.
776 08 $iPrint version:$tAnalogue-based drug discovery III.$dWeinheim : Wiley-VCH, [2013]$z9783527330737$w(OCoLC)825555931
988 $a20140710
906 $0OCLC