MARC Record from harvard_bibliographic_metadata

LEADER: 03314nam a22004575a 4500
001 014131543-1
005 20140905184833.0
008 140708s2014 gw | s ||0| 0|eng d
020 $a9783319044354
020 $a9783319044354
020 $a9783319044347
024 7 $a10.1007/978-3-319-04435-4$2doi
035 $a(Springer)9783319044354
040 $aSpringer
050 4 $aQD415-436
072 7 $aPNN$2bicssc
072 7 $aSCI013040$2bisacsh
082 04 $a547$223
100 1 $aNenajdenko, Valentine,$eeditor.
245 10 $aFluorine in Heterocyclic Chemistry Volume 2 :$b6-Membered Heterocycles /$cedited by Valentine Nenajdenko.
264 1 $aCham :$bSpringer International Publishing :$bImprint: Springer,$c2014.
300 $aX, 760 p. 1896 illus., 9 illus. in color.$bonline resource.
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
347 $atext file$bPDF$2rda
505 0 $aSynthesis of Fluorinated Pyridines -- Fluorinated Quinolines: Synthesis, Properties and Applications -- Fluoroquinolones: Synthesis and Application -- Syntheses, Properties and Applications of Fluorinated Isoquinolines -- Fluorinated Pyrones, Chromones and Coumarins -- Chemistry of Fluorinated Diazines -- Fluorine-Containing Diazines in Medicinal Chemistry and Agrochemistry -- Fluorinated Triazines -- Chemistry of Fluorinated Purines.
520 $aThis two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing  6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.
650 20 $aPharmaceutical chemistry.
650 20 $aBiomedical materials.
650 20 $aChemistry, Organic.
650 10 $aChemistry.
650 0 $aBiomedical materials.
650 0 $aChemistry.
650 0 $aToxicology.
650 0 $aChemistry, Organic.
650 0 $aBiochemistry.
650 24 $aPharmacology/Toxicology.
776 08 $iPrinted edition:$z9783319044347
988 $a20140802
906 $0VEN