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037 $a978-1-4020-6190-5$bSpringer$nhttp://www.springerlink.com
050 4 $aQP535.C2$bC35 2007eb
060 4 $aW1$bSU14 v.45 2007
060 4 $aQU 55.7
072 7 $aSCI$x007000$2bisacsh
082 04 $a572.516$222
245 00 $aCalcium signalling and disease :$bmolecular pathology of calcium /$cedited by Ernesto Carafoli and Marisa Brini.
260 $aNew York :$bSpringer,$c2007.
300 $a1 online resource (xii, 566, [26] pages) :$billustrations (some color)
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
490 1 $aSubcellular biochemistry ;$vv. 45
504 $aIncludes bibliographical references and index.
505 0 $aAnnexinopathies / M.J. Hayes [and others] -- Calpains and human disease / I. Bertipaglia and E. Carafoli -- Gelsolin and diseases / L. Spinardi and W. Witke -- Guanylate cyclase-activating proteins and retina disease / W. Baehr and K. Palczewski -- Pathologies involving the S100 proteins and rage / C.W. Heizmann [and others] -- The calcium-sensing receptor: Physiology, pathophysiology and CaR-based therapeutics / E.M. Brown -- Physiological roles of the Ca2+/CaM-dependent protein kinase cascade in health and disease / J. Colomer and A.R. Means -- Calcium channelopathies: Voltage-gated calcium channels / P.J. Adams and T.P. Snutch -- TRP channels in disease / S.E. Jordt and B.E. Ehrlich -- Diseases associated with altered ryanodine receptor activity / W.J. Durham [and others] -- Inositol 1,4,5-tripshosphate receptor, calcium signalling and Huntington's disease / I. Bezprozvanny -- SERCA pumps and human diseases / A. Hovnanian -- The plasma membrane calcium ATPase and disease / B.L. Tempel and D.J. Shilling -- Diseases involving the Golgi calcium pump / J. Vanoevelen [and others] -- Calcium signalling and cancer cell growth / T. Capiod [and others] -- Calcium misregulation and the pathogenesis of muscular dystrophy / F.W. Hopf [and others] -- Calcium and cell death / A. Verkhratsky -- Calcium and cell death: The mitochondrial connection / P. Bernardi and A. Rasola -- Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models / K.N. Green [and others] -- Calcium and cardiomyopathies / E.G. Kranias and D.M. Bers -- Calcium signalling and calcium transport in bone disease / H.C. Blair [and others].
588 0 $aPrint version record.
520 $aThis topic is a new entry in the area of cellular calcium signaling: yet, it now spans the entire area, with discoveries that cover both genetic and acquired pathologies, even offering glimpses in the direction of therapy. Cellular calcium homeostasis, and thus calcium signalling, is mainly regulated by membrane intrinsic proteins and calcium sensor proteins. Both classes may be involved in pathological processes that affect both human and animals, ranging from common and important diseases (e.g. migraine, diabetes, epilepsia, manic depression, infertility, various types of cancer, Alzheimer's disease, muscular dystrophy) to rare genetic conditions (e.g., a number of genetic heart conditions, autoimmune retinopathies, night blindness, hereditary amyloid polyneuropathy, malignant hyperthermia, cerebellar ataxia, atherothrombotic disease). Clearly, the topic has now become not only very large, but also very stimulating. Its extensive critical coverage is likely to eventually stimulate fruitful interdisciplinary discussions.
650 0 $aCalcium$xPathophysiology.
650 0 $aCalcium$xPhysiological effect.
650 2 $aCalcium Signaling.
650 2 $aCalcium Channels.
650 2 $aCalcium$xphysiology.
650 22 $aCalcium Metabolism Disorders.
650 6 $aCalcium$xEffets physiologiques.
650 6 $aCanaux à calcium.
650 6 $aCalcium$xMétabolisme, Troubles du.
650 6 $aCalcium$xPhysiopathologie.
650 7 $aSCIENCE$xLife Sciences$xBiochemistry.$2bisacsh
650 7 $aBiomédecine.$2eclas
650 7 $aSciences de la vie.$2eclas
650 7 $aCalcium$xPhysiological effect.$2fast$0(OCoLC)fst00844050
655 4 $aElectronic books.
700 1 $aCarafoli, Ernesto.
700 1 $aBrini, Marisa.
776 08 $iPrint version:$tCalcium signalling and disease.$dNew York : Springer, 2007$z9781402061905$z1402061900$w(OCoLC)154712061
830 0 $aSub-cellular biochemistry ;$vv. 45.
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