Record ID | ia:cancersusceptibi0653unse |
Source | Internet Archive |
Download MARC XML | https://archive.org/download/cancersusceptibi0653unse/cancersusceptibi0653unse_marc.xml |
Download MARC binary | https://www.archive.org/download/cancersusceptibi0653unse/cancersusceptibi0653unse_meta.mrc |
LEADER: 07831cam 2201153Ia 4500
001 ocn664246508
003 OCoLC
005 20200507041137.0
008 100916s2010 njua ob 001 0 eng d
006 m o d
007 cr cn|||||||||
040 $aGW5XE$beng$epn$cGW5XE$dOCLCQ$dCUS$dOCLCQ$dSCB$dOCLCQ$dUBY$dOCLCA$dOCLCF$dOCLCQ$dYDXCP$dEUW$dOCLCQ$dVT2$dOCLCO$dOCLCA$dMERER$dOCLCO$dLVT$dLIP$dOTZ$dOCLCQ$dOCLCO$dOCLCA$dBUF$dOCLCQ$dCASUM$dOCLCQ$dU3W$dOCLCO$dAU@$dOCLCA$dYOU$dOCLCA$dOCLCQ$dOCLCO$dU3G$dESU$dSCB$dOCLCQ$dWURST$dOCLCA
015 $aGBB060991$2bnb
016 7 $a015551384$2Uk
019 $a662668678$a771209429$a964912625$a967616522$a990479904$a1005826823$a1045258335$a1050754542$a1058942533$a1081268360$a1086998982
020 $a9781607617594
020 $a1607617595
020 $z9781607617587$q(hbk.)
020 $z1607617587$q(hbk.)
024 7 $a10.1007/978-1-60761-759-4$2doi
035 $a(OCoLC)664246508$z(OCoLC)662668678$z(OCoLC)771209429$z(OCoLC)964912625$z(OCoLC)967616522$z(OCoLC)990479904$z(OCoLC)1005826823$z(OCoLC)1045258335$z(OCoLC)1050754542$z(OCoLC)1058942533$z(OCoLC)1081268360$z(OCoLC)1086998982
037 $a978-1-60761-758-7$bSpringer$nhttp://www.springerlink.com
050 4 $aRC268.4$b.C36 2010
060 4 $aQZ 202$bC219 2010
072 7 $aMJCL$2bicssc
072 7 $aMED062000$2bisacsh
082 04 $a616.994042$222
245 00 $aCancer susceptibility :$bmethods and protocols /$cvolume editor, Michelle Webb.
260 $aTotowa, N.J. :$bHumana ;$aLondon :$bSpringer [distributor],$c2010.
300 $a1 online resource
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
347 $atext file$bPDF$2rda
490 1 $aMethods in molecular biology ;$v653
505 0 $aThe identification of colon cancer susceptibility genes by using genome-wide scans -- Prioritizing candidate genetic modifiers of BRCA1 and BRCA2 using a combinatorial analysis of global expression and polymorphism association studies of breast cancer -- Microarray-based comparative genomic hybridization (array-CGH) as a useful tool for identifying genes involved in Glioblastoma (GB) -- Multiplex Amplifiable Probe Hybridization (MAPH) methodology as an alternative to comparative genomic hybridization (CGH) -- Utilizing Saccharomyces cerevisiae to identify aneuploidy and cancer susceptibility genes -- Computational identification of cancer susceptibility loci -- Digital candidate gene approach (DigiCGA) for identification of cancer genes -- The use of denaturing high performance liquid chromatography (DHPLC) for mutation scanning of hereditary cancer genes -- Enhanced mismatch mutation analysis: simultaneous detection of point mutations and large scale rearrangements by capillary electrophoresis, application to BRCA1 and BRCA2 -- Economical protocol for combined single-strand conformation polymorphism and heteroduplex analysis on a standard capillary electrophoresis apparatus -- Mutational screening of hMLH1 and hMSH2 that confer inherited colorectal cancer susceptibility using denature gradient gel electrophoresis (DGGE) -- s-RT-MELT: a novel technology for mutation screening -- Zoom-in array comparative genomic hybridization (aCGH) to detect germline rearrangements in cancer susceptibility genes -- Development of a scoring system to screen for BRCA1/2 mutations -- Use of splicing reporter minigene assay to evaluate the effect on splicing of unclassified genetic variants -- Functional analysis of human BRCA2 variants using a mouse embryonic stem cell-based assay -- Developing functional assays for BRCA1 unclassified variants.
588 0 $aPrint version record.
504 $aIncludes bibliographical references and index.
520 $aOver the past two decades, spectacular advances have been made in our understanding of the molecular genetics of cancer, leading to the pursuit of identifying genes that, when mutated, result in an increased susceptibility to the disease. In Cancer Susceptibility: Methods and Protocols, experts in the field bring together the most recent technological developments for identifying and screening cancer susceptibility genes. Divided into two clear sections, the book begins with gene identification, which updates and informs scientists working at identifying novel cancer susceptibility genes, while the second part deals with mutation screening technologies that aid scientists and clinicians working to translate this knowledge into the clinic. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Susceptibility: Methods and Protocols is a timely collection that seeks to provide researchers with the tools to predict and combat this terrible disease.
546 $aEnglish.
650 0 $aCancer$xSusceptibility.
650 0 $aCancer$xGenetic aspects.
650 2 $aGenetic Services.
650 2 $aDiagnostic Techniques and Procedures.
650 2 $aDiagnostic Services.
650 2 $aPublication Formats
650 2 $aInvestigative Techniques
650 2 $aGenetic Techniques.
650 2 $aGenotype.
650 2 $aDisease Susceptibility.
650 2 $aBiology.
650 2 $aGenetic Predisposition to Disease.
650 2 $aLaboratory Manuals
650 2 $aGenetic Testing.
650 2 $aMethods.
650 2 $aGenetics.
650 2 $aAnalytical, Diagnostic and Therapeutic Techniques and Equipment
650 2 $aDisease Attributes
650 2 $aDiagnosis.
650 2 $aPublication Characteristics
650 2 $aBiological Science Disciplines.
650 2 $aHealth Services.
650 2 $aPreventive Health Services.
650 2 $aGenetic Phenomena.
650 2 $aNatural Science Disciplines.
650 2 $aPhenomena and Processes
650 2 $aCommunity Health Services.
650 2 $aHealth Care Facilities, Manpower, and Services
650 2 $aPathologic Processes.
650 2 $aPathological Conditions, Signs and Symptoms
650 2 $aDelivery of Health Care.
650 2 $aDisciplines and Occupations
650 2 $aDisease.
650 7 $aCancer$xGenetic aspects.$2fast$0(OCoLC)fst00845368
650 7 $aCancer$xSusceptibility.$2fast$0(OCoLC)fst00845535
650 7 $aMedicine.$2hilcc
650 7 $aOncology.$2hilcc
650 7 $aHealth & Biological Sciences.$2hilcc
653 00 $aneoplasms
653 00 $abiomedische wetenschappen
653 00 $abiomedicine
653 00 $ahumane genetica
653 00 $ahuman genetics
653 10 $aMedicine (General)
653 10 $aGeneeskunde (algemeen)
655 4 $aElectronic books.
700 1 $aWebb, Michelle.
776 08 $iPrint version:$tCancer susceptibility.$dTotowa, N.J. : Humana ; London : Springer [distributor], 2010$z9781607617587$z1607617587$w(OCoLC)615896345
830 0 $aMethods in molecular biology (Clifton, N.J.) ;$vv. 653.$x1064-3745
856 40 $3SpringerLink$uhttps://doi.org/10.1007/978-1-60761-759-4
856 40 $3SpringerLink$uhttps://link.springer.com/book/10.1007/978-1-60761-759-4
856 40 $3SpringerLink$uhttps://link.springer.com/book/10.1007/978-1-60761-758-7
856 40 $3SpringerLink$uhttp://www.library.yorku.ca/e/resolver/id/2480073$zAn electronic book accessible through the World Wide Web; click for information
856 40 $uhttp://www.library.yorku.ca/e/resolver/id/2480074
938 $aYBP Library Services$bYANK$n3531816
029 1 $aAU@$b000061126170
029 1 $aNZ1$b15212423
994 $aZ0$bP4A
948 $hNO HOLDINGS IN P4A - 151 OTHER HOLDINGS