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LEADER: 02940cam a22003494a 4500
001 2006028271
003 DLC
005 20071026082513.0
008 060824s2007 paua b 001 0 eng
010 $a 2006028271
020 $a9780781782104
020 $a0781782104
035 $a(DNLM)101285830
040 $aDNLM/DLC$cDLC$dDLC
042 $apcc
050 00 $aR853.C55$bD47 2007
082 00 $a610.72$222
245 00 $aDesigning clinical research /$cStephen B. Hulley ... [et al.].
250 $a3rd ed.
260 $aPhiladelphia, PA :$bLippincott Williams & Wilkins,$cc2007.
300 $axv, 367 p. ill. ;$c26 cm.
504 $aIncludes bibliographical references and index.
505 0 $aGetting started: the anatomy and physiology of clinical research / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- Conceiving the research question / Steven R. Cummings, Warren S. Browner, and Stephen B. Hulley -- Choosing the study subjects: specification, sampling, and recruitment / Stephen B. Hulley, Thomas B. Newman, and Steven R. Cummings -- Planning the measurements: precision and accuracy / Stephen B. Hulley and Steven R. Cummings -- Getting ready to estimate sample size: hypotheses and underlying principles / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- Estimating sample size and power: applications and examples / Warren S. Browner, Thomas B. Newman, and Stephen B. Hulley -- Designing an observational study: cohort studies / Steven R. Cummings, Thomas B. Newman, and Stephen B. Hulley -- Designing an observational study: cross-sectional and case-control studies / Thomas B. Newman ... [et al.] -- Enhancing causal inference in observational studies / Thomas B. Newman, Warren S. Browner, and Stephen B. Hulley --
505 0 $aDesigning a randomized blinded trial / Steven R. Cummings, Deborah Grady, and Stephen B. Hulley -- Alternative trial designs and implementation issues / Deborah Grady, Steven R. Cummings, and Stephen B. Hulley -- Designing studies of medical tests / Thomas B. Newman, Warren S. Browner, and Steven R. Cummings -- Research using existing databases: secondary data analysis, ancillary studies, and systematic reviews / Deborah Grady and Norman Hearst -- Addressing ethical issues / Bernard Lo -- Designing questionnaires and interviews / Steven R. Cummings and Stephen B. Hulley -- Data management / Michael A. Kohn -- Implementing the study: pretesting, quality control, and protocol revisions / Stephen B. Hulley and Steven R. Cummings.
650 0 $aClinical trials.
650 0 $aMedicine$xResearch$xMethodology.
650 0 $aEpidemiology$xResearch$xMethodology.
650 12 $aEpidemiologic Methods.
650 22 $aResearch Design.
700 1 $aHulley, Stephen B.
856 41 $3Table of contents only$uhttp://www.loc.gov/catdir/toc/ecip0619/2006028271.html
856 42 $3Publisher description$uhttp://www.loc.gov/catdir/enhancements/fy0712/2006028271-d.html