MARC record from Internet Archive

LEADER: 06613cam 2200913Mu 4500
001 ocn923269014
003 OCoLC
005 20190104215515.0
008 151010s2001 dcu ob 000 0 eng d
006 m o d
007 cr |n|||||||||
040 $aEBLCP$beng$epn$cEBLCP$dOCLCQ$dMERUC$dOCLCQ$dXFH$dOCLCF$dOCLCQ$dNJR$dOCLCO$dZCU$dOCLCO$dOCLCA$dU3W$dOCLCO$dOCLCQ$dOCLCO$dICG$dAU@$dOCLCQ$dOCLCA$dLVT$dOCLCA
019 $a994400892$a1058521996
020 $a9780309567619
020 $a0309567610
020 $a0309073162
020 $a9780309073165
020 $a1280185090
020 $a9781280185090
020 $a9786610185092
020 $a6610185093
035 $a(OCoLC)923269014$z(OCoLC)994400892$z(OCoLC)1058521996
043 $an-us---
050 4 $aRA1224.2.N385 2001eb
082 04 $a616.65071
100 1 $aToxicity, Subcommittee on Reproductive and Developmental.
245 10 $aEvaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity.
260 $aWashington :$bNational Academies Press,$c2001.
300 $a1 online resource (262 pages).
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
490 1 $aThe compass series
588 0 $aPrint version record.
505 0 $a""EVALUATING CHEMICAL AND OTHER AGENT EXPOSURES FOR REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""Copyright""; ""Preface""; ""Contents""; ""Abbreviations""; ""EVALUATING CHEMICAL AND OTHER AGENT EXPOSURES FOR REPRODUCTIVE AND DEVELOPMENTAL TOXICITY""; ""Summary""; ""CONCLUSIONS AND RECOMMENDATIONS""; ""Evaluative Process""; ""Assessing the Available Data""; ""Integration of Toxicity and Exposure Information""; ""Insufficient Data Sets""; ""Application of the Evaluative Process""; ""Sources of Information""; ""Research Recommendations""; ""1 Introduction ""; ""SUBCOMMITTEE'S TASK""
505 8 $a""ORGANIZATION OF THE REPORT""""2 The Evaluative Process: Part I. Assessing the Available Data ""; ""PRINCIPLES AND OBJECTIVES""; ""Use of Data and Judgment""; ""Weight of Evidence""; ""Threshold Assumption""; ""Narrative Statement""; ""Certainty""; ""Use All Relevant, Acceptable Data""; ""Qualities and Limitations of Reproductive and Developmental Toxicity Studies""; ""Characterizing Data""; ""Expert Review Team""; ""GENERAL DESCRIPTION""; ""DETAILS OF THE EVALUATIVE PROCESS""; ""Exposure Data""; ""General Toxicological and Biological Parameters""; ""Chemistry""; ""Basic Toxicity""
505 8 $a""Acute Studies""""Repeated-Dose Studies""; ""Genetic Toxicity""; ""Pharmacokinetics""; ""Reproductive and Developmental Toxicity""; ""Human Data""; ""Weighing the Evidence""; ""Case Reports and Clinical Series""; ""Assessing Causality in Human Studies""; ""Experimental Animal Toxicity""; ""Utility and Limitations""; ""Adverse Effect""; ""3 The Evaluative Process: Part II. Integration of Toxicity and Exposure Information ""; ""INTERPRETATION OF TOXICITY DATA""; ""Default Assumptions To Be Considered in Assessing Reproductive and Developmental Toxicity Risk""; ""Absorption""
505 8 $a""Cross-Species Extrapolation""""Exposure Duration""; ""Windows of Vulnerability""; ""Additivity""; ""QUANTITATIVE EVALUATION""; ""Identification of the NOAEL and LOAEL""; ""Calculation of the Benchmark Dose""; ""Duration Adjustment""; ""Uncertainty Factors""; ""Calculation of the Unlikely Effect Level""; ""Calculation of the Margin of Exposure (MOE)""; ""Assessing a Degree of Concern""; ""Application of Reproductive and Developmental Toxicity Data to Various Exposure Scenarios""; ""Critical Data Needs""; ""SUMMARY""; ""4 Incomplete or Insufficient Data Sets ""
505 8 $a""PRINCIPLES TO MINIMIZE RISK""""PRACTICAL APPLICATION""; ""REDUCING UNCERTAINTY""; ""5 Recommendations ""; ""GENERAL RECOMMENDATIONS""; ""RESEARCH RECOMMENDATIONS""; ""References""; ""Appendixes""; ""Appendix A Application of the Recommended Evaluative Process to Specific Chemicals ""; ""JP-8 JET FUEL""; ""Exposure Data""; ""General Toxicological and Biological Parameters""; ""Lethality""; ""Acute Studies""; ""Human Studies""; ""Experimental Animal Studies""; ""Repeated-Dose Studies""; ""Human Studies""; ""Experimental Animal Studies""; ""Cancer""; ""Genetic Toxicity""
500 $a""Disposition and Pharmacokinetics""
546 $aEnglish.
504 $aIncludes bibliographical references (pages 92-114).
650 0 $aReproductive toxicology.
650 0 $aDevelopmental toxicology.
650 0 $aToxicity testing.
650 7 $aDevelopmental toxicology.$2fast$0(OCoLC)fst00891841
650 7 $aReproductive toxicology.$2fast$0(OCoLC)fst01095012
650 7 $aToxicity testing.$2fast$0(OCoLC)fst01153336
650 2 $aEnvironmental Pollutants.
650 2 $aReproduction.
650 2 $aEnvironmental Exposure.
650 2 $aTeratogens.
650 2 $aAbnormalities, Drug-Induced.
650 2 $aCongenital Abnormalities.
650 2 $aReproductive Physiological Phenomena.
650 2 $aEnvironmental Pollution.
650 2 $aToxic Actions.
650 2 $aNoxae.
650 2 $aCongenital, Hereditary, and Neonatal Diseases and Abnormalities.
650 2 $aChemical Actions and Uses.
650 2 $aPublic Health.
650 2 $aEnvironment and Public Health.
650 2 $aChemicals and Drugs.
650 2 $aDisease.
650 2 $aReproductive and Urinary Physiological Phenomena.
650 2 $aDelivery of Health Care.
650 2 $aPhenomena and Processes.
655 4 $aElectronic books.
700 1 $aStaff, National Research Council.
776 08 $iPrint version:$aToxicity, Subcommittee on Reproductive and Developmental.$tEvaluating Chemical and Other Agent Exposures for Reproductive and Developmental Toxicity.$dWashington : National Academies Press, ℗♭1900$z9780309073165
830 0 $aCompass series (Washington, D.C.)
856 40 $3Ebook Library$uhttp://public.eblib.com/choice/publicfullrecord.aspx?p=3377205
856 40 $3ProQuest Ebook Central$uhttp://public.ebookcentral.proquest.com/choice/publicfullrecord.aspx?p=3377205
856 40 $uhttps://www.nap.edu/10007$z<img src="/screens/gifs/go4.gif" alt="Go button" border="0"width="21"height="21"hspace="7" align="middle">View this e-book online via National Academies Press (2001)
856 40 $uhttps://ebookcentral.proquest.com/lib/columbia/detail.action?docID=3377205$zEbook Central Academic Complete
938 $aEBL - Ebook Library$bEBLB$nEBL3377205
029 1 $aDEBBG$bBV044107860
994 $aZ0$bP4A
948 $hNO HOLDINGS IN P4A - 323 OTHER HOLDINGS