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019 $a816509779$a1124324888
020 $a9780123822284$q(electronic bk.)
020 $a0123822289$q(electronic bk.)
020 $z9780123822277
020 $z9780124159389
020 $z0124159389
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020 $z0124159370
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060 4 $aQZ 50$bG33535 2013
072 7 $aHEA$x039060$2bisacsh
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082 04 $a616.042$223
245 00 $aGenomic and personalized medicine /$cedited by Geoffrey S. Ginsburg and Huntington F. Willard.
250 $a2nd ed.
260 $aLondon :$bElsevier/Academic Press,$c©2013.
300 $a1 online resource (2 volumes (xxxv, 1305 pages)) :$billustrations
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
500 $aFirst edition 2009.
500 $aTitle from PDF title page (viewed on Dec. 4, 2012).
500 $aTitle from pdf title page (viewed November 8, 2012).
504 $aIncludes bibliographical references and index.
505 0 $aThe Human Genome: A Window on Human Genetics, Biology, and Medicine -- Mapping the Functional Genome: The ENCODE and Roadmap Epigenomics Projects -- Population Perspectives on Genome Variation and Complex Disease -- Gene-Environment Interactions: Eco-Genetics and Toxicogenomics -- Systems Biology and Systems Medicine -- Personal Genomics -- Whole-Genome Sequencing: New Technologies, Approaches, and Applications -- Human Genome Variation Discovery via Exome and Whole-Genome Sequencing -- Clinical Genome Sequencing -- Structural Genomic Variation in the Human Genome -- Clinical Applications of Whole-Genome Chromosomal Microarray Analysis -- Transcriptomics in the Age of Ultra High-Throughput Sequencing -- Quantitative Proteomics in Genomic Medicine -- The Human Microbiome and Personalized Medicine -- Glycomics, Glycobiology, and Glyco-Medicine -- Genome-Wide RNA Interference Screening -- Application of Human Genome Information to Clinical Practice -- Genomic, Personalized Medicine and Public Health -- Biospecimen Banking in the Post-Genome Era -- Designing Genomics-Based Clinical Studies -- Genomic Biomarkers in Human Population Studies -- Validation of Candidate Protein Biomarkers -- Translational Bioinformatics for Genomic Medicine -- Electronic Health Records in Genomic Medicine -- Clinical Implementation of Genomic Medicine in Primary Care -- Family History and Health Risk Assessment -- Clinical Decision Support -- Knowledge Management to Support Personalized Healthcare -- Delivery of Personalized Medicine in an Integrated Healthcare System -- Pharmacogenomics in Drug Discovery and Development -- Pharmacogenetics and Pharmacogenomics -- Point-of-Care Devices -- Patient-Specific Pluripotent Stem Cells -- Overview of Policy, Ethical and Social Considerations in Genomic and Personalized Medicine -- Informed Consent -- Educational Issues and Strategies for Genomic Medicine -- Regulatory Issues for Genomic Technologies -- Challenges and Regulation of Direct to Consumer Testing -- Economic Issues and Genomic Medicine -- Strategic Issues in the Adoption of Genome-Based Diagnostics -- Reimbursement -- Genomics and Patents: A Practical Guide for Genome Scientists and Clinical Researchers -- Public-Private Partnerships in Biomarker Research -- Hypertension -- Lipoprotein Disorders -- Coronary Artery Disease and Myocardial Infarction -- Atherosclerosis, Vulnerable Plaques, and Acute Coronary Syndromes -- Heart Failure -- Cardiac Transplant Rejection -- Hypertrophic Cardiomyopathies.
505 0 $aArrhythmias -- Hemostasis and Thrombosis -- Peripheral Arterial Disease -- Congenital Heart Disease -- Perioperative Genomics -- Stroke -- Lymphomas -- Leukemias -- Lung Cancer -- Breast Cancer -- Ovarian Cancer -- Colorectal Cancer -- Prostate Cancer -- Head and Neck Cancer -- Brain Tumors and Gliomas -- Melanoma -- Metastatic Cancer -- Bioinformatics in Personalized Cancer Care -- Diagnostic-Therapeutic Combinations -- Autoimmune Disorders -- Rheumatoid Arthritis -- Multiple Sclerosis -- Inflammatory Bowel Disease -- Asthma -- Chronic Obstructive Pulmonary Disease -- Interstitial Lung Disease -- Peptic Ulcer Disease -- Cirrhosis -- Systemic Sclerosis -- Systemic Lupus Erythematosus -- Osteoarthritis -- Diabetes -- The Metabolic Syndrome -- Neuroscience and the Genomic Revolution: An Overview -- Alzheimer's Disease -- Parkinson's Disease -- Epilepsy -- Schizophrenia and Bipolar Disorder -- Depression -- Autism Spectrum Disorders -- Eye Diseases -- Glaucoma -- Diagnosis and Classification of Pathogens -- Host-Pathogen Interactions -- Microbial Vaccine Development -- Bacterial Infections -- Emerging Viral Infections -- Sepsis -- Viral Hepatitis -- Malaria -- HIV Pharmacogenetics and Pharmacogenomics.
520 $aThis two-volume set provides an in-depth look at one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. The inclusion of the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more presents this book as an essential tool for both students and specialists across many biological and medical disciplines, including human genetics and genomics, oncology, neuroscience, cardiology, infectious disease, molecular medicine, and biomedical science, as well as health policy disciplines focusing on ethical, legal, regulatory and economic aspects of genomics and medicine. Volume One Includes: Principles, Methodology and Translational Approaches, takes readers on the journey from principles of human genomics to technology, informatic and computational platforms for genomic medicine, as well as strategies for translating genomic discoveries into advances in personalized clinical care. Volume Two Includes: Genome Discoveries and Clinical Applications presents the latest developments in disease-based genomic and personalized medicine. With chapters dedicated to cardiovascular disease, oncology, inflammatory disease, metabolic disease, neuropsychiatric disease, and infectious disease, this work provides the most comprehensive guide to the principles and practice of genomic and personalized medicine. * Contributions from leaders in the field provide unparalleled insight into current technologies and applications in clinical medicine. * Full colour throughout enhances the utility of this work as the only available comprehensive reference for genomic and personalized medicine. * Discusses scientific foundations and practical applications of new discoveries, as well as ethical, legal/regulatory, and social issues related to the practice of genomic medicine.
650 0 $aMedical genetics.
650 0 $aGenomics.
650 0 $aProteomics.
650 2 $aGenetics, Medical$xmethods.
650 2 $aGenomics$xmethods.
650 2 $aProteomics$xmethods.
650 7 $aHEALTH & FITNESS$xDiseases$xGenetic.$2bisacsh
650 7 $aMEDICAL$xGenetics.$2bisacsh
650 7 $aGenomics.$2fast$0(OCoLC)fst00940228
650 7 $aMedical genetics.$2fast$0(OCoLC)fst01014133
650 7 $aProteomics.$2fast$0(OCoLC)fst01079785
655 0 $aElectronic books.
655 4 $aElectronic books.
700 1 $aGinsburg, Geoffrey S.
700 1 $aWillard, Huntington F.
776 08 $iPrint version:$tGenomic and personalized medicine.$b2nd ed.$dAmsterdam : Elsevier/Academic Press, 2013$z9780123822277$w(OCoLC)824605143
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856 40 $uhttps://archive.org/details/genomicpersonali0002unse$zFree eBook from the Internet Archive
856 40 $uhttps://openlibrary.org/books/OL28483037M$zAdditional information and access via Open Library
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