MARC record from Internet Archive

LEADER: 07094cam 22006494a 4500
001 ocm65617482
003 OCoLC
005 20200423235802.0
008 060331s2007 maua b 001 0 eng
010 $a 2006010791
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060 00 $a2007 B-687
060 10 $aQU 325$bK47h 2007
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082 00 $a612.6/4$222
100 1 $aKiessling, Ann A.
245 10 $aHuman embryonic stem cells /$cAnn A. Kiessling, Scott C. Anderson.
250 $a2nd ed.
260 $aSudbury, Mass. :$bJones and Bartlett Publishers,$c℗♭2007.
300 $axii, 280 pages :$billustrations ;$c23 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
490 1 $aJones and Bartlett topics in biology
504 $aIncludes bibliographical references and index.
505 0 $apt. I. The basics -- 1. The nature of stem cells -- Overview -- Adult stem cells -- Sidebar : bone marrow transplantation / E. Donnell Thomas -- Fetal tissue stem cells -- Embryonic stem cells -- Parthenote stem cells -- Nuclear transplant stem cells -- Human cloning -- Summary -- 2. The dividing cell -- Overview -- The cell cycle -- Stimulating cell division -- Gene expression : transcription and translation -- Molecular biology of the cell cycle -- Sidebar : cell cycle regulators : Lee Hartwell, Paul Nurse, and Tim Hunt -- Summary -- pt. II. Egg specific functions -- 3. The egg -- Overview -- Egg growth -- Oocyte meiosis -- Assisted reproductive technologies -- Molecular biology of oocyte meiosis -- Sidebar : cMos activity : metaphase II arrest -- Summary -- 4. The activated egg -- Overview -- Spontaneous egg activation -- Artificial egg activation -- Egg activation by sperm -- Sidebar : activation of human eggs : in vitro fertilization and cleavage of human ovarian eggs -- Egg activation after nuclear transplantation -- Molecular biology of egg activation -- Summary -- 5. The zygote -- Overview -- The pronuclear stage egg -- Manipulation of the zygote -- Parthenotes -- Haploid parthenotes -- Sidebar : transgenic mice : introduction of foreign genes into zygotes -- Diploid parthenotes -- Molecular Biology of zygotes -- Summary -- 6. Blastomere cleavage -- Overview -- The first cleavage -- The two-cell stage -- The second cleavage -- Fragmented cleavages -- The third cleavage -- The fourth and fifth cleavages -- Embryo development in laboratory conditions -- Sidebar : Development of tissue culture media -- Molecular Biology of blastomere cleavage -- Summary -- 7. Early nuclear transfer technology -- Overview -- Sidebar : developmental potential of transplanted nuclei -- Transfer of nuclei into frog eggs -- Gene expression : transcription and translation -- Transcription and translation in frog eggs -- Reprogramming a nucleus -- Transplantation of embryonic nuclei into fertilized eggs -- Summary.
505 0 $apt. III Embryonic stem cells -- 8. The blastocyst and inner cell mass cells -- Overview -- Equivalence groups -- The blastocyst -- The inner cell mass -- Implantation -- Blastocyst development in vitro -- Embryonic stem cells -- Chimeras -- Sidebar : knockout mice -- Summary -- 9. Organogenesis -- Overview -- The second week -- The third week -- The fourth week -- Fifth and sixth weeks -- Primordial germ cells migration -- Sidebar : primordial germ cells and embryonal carcinoma cells -- Fetal tissue stem cells -- Parthenogenesis -- Summary -- 10. Mammalian nuclear transfer technology -- Overview -- Nuclear transplantation and the cell cycle of fertilized eggs -- Transplantation of embryonic nuclei into unfertilized eggs -- Transplantation of somatic cell nuclei into unfertilized eggs -- Animal cloning -- Challenges in cloning human pluripotent stem cells -- Sidebar : somatic cell nuclear transfer in humans : pronuclear and early embryonic development -- Summary -- pt. IV. Human stem cells -- 11. Adult and fetal stem cells -- Overview -- Adult stem cells -- Sidebar : hematopoietic and cord blood stem cells -- Fetal stem cells -- Summary -- 12. Pluripotent stem cells -- Overview -- Human embryonic stem cells -- Sidebar : human embryonic stem cells -- Human parthenote stem cells -- Human nuclear transplantation stem cells -- The process of stem cell differentiation -- Summary -- pt. V. Stem cell therapies -- 13. Neurogenerative diseases -- Overview -- Parkinson's disease -- Alzheimer's disease -- Multiple sclerosis -- Other brain syndromes -- Spinal cord injury -- Summary -- 14. Tissue systems failures -- Overview -- Diabetes -- Type 1 diabetes -- Type 2 diabetes -- Cardiomyopathy -- Kidney failure -- Liver failure -- Cancer -- Hemophilia -- Other tissue failures -- Summary -- pt. VI. Human embryonic stem cells and society -- 15. The religious, legal, ethical and scientific debate -- Overview -- The religious debate -- The legal debate -- The ethical debate -- The scientific debate -- The future of the debate -- Summary -- Glossary.
520 $aThe second edition of Kiessling and Anderson's text, Human Embryonic Stem Cells, continues to address the social, legal and ethical debates resulting from the Bush Administrations restriction of federal funding for embryonic stem cell therapy. The emerging field of human embryonic stem cell biomedicine crosses many disciplinary boundaries -- cell biology, reproductive biology, embryology, molecular biology, endocrinology, immunology, fetal medicine, transplantation medicine, and surgery. This single reference provides basic information from these multiple disciplines as it pertains to the science of stem cells.
650 0 $aEmbryonic stem cells.
650 12 $aStem Cells.
650 22 $aEmbryo, Mammalian$xcytology.
650 6 $aCellules souches embryonnaires.
650 7 $aEmbryonic stem cells.$2fast$0(OCoLC)fst00908443
700 1 $aAnderson, Scott,$d1951-
776 08 $iOnline version:$aKiessling, Ann A.$tHuman embryonic stem cells.$b2nd ed.$dSudbury, Mass. : Jones and Bartlett Publishers, ℗♭2007$w(OCoLC)974382350
830 0 $aJones and Bartlett topics in biology.
856 41 $3Table of contents$uhttp://catdir.loc.gov/catdir/toc/ecip0611/2006010791.html
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