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LEADER: 03080cam a22004457a 4500
001 2011935731
003 DLC
005 20140203112850.0
008 110803s2012 nyua b 001 0 eng
010 $a 2011935731
016 7 $a101574564$2DNLM
016 7 $a015842043$2Uk
020 $a9781461405979 (alk. paper)
020 $a1461405971 (alk. paper)
020 $a9781461405986 (e-ISBN)
020 $a146140598X (e-ISBN)
035 $a(OCoLC)ocn731918445
040 $aNLM$beng$cNLM$dBTCTA$dUKMGB$dYDXCP$dOHX$dLTL$dDLC
042 $anlmcopyc$alccopycat
050 00 $aQP552.S65$bI568 2012
060 00 $a2011 L-647
060 10 $aQU 107
082 00 $a572/.696$223
245 00 $aInsulin-like growth factors and cancer :$bfrom basic biology to therapeutics /$cDerek LeRoith, editor.
260 $aNew York :$bHumana Press,$cc2012.
300 $axii, 284 p. :$bill. (some col.) ;$c24 cm.
490 1 $aCancer drug discovery and development
504 $aIncludes bibliographical references and index.
505 0 $aEpidemiology of IGF-1 and cancer / Katharina Nimptsch and Eward Giovannucci -- Aging and cancer : the IGF- I connection / Kalina Biernacka, Claire Perks, and Jeff Holly -- Obesity, type 2 diabetes and cancer / Rosalyn D. Ferguson and Derek LeRoith -- IGF system and breast cancer / Marc A. Becker and Douglas Yee -- The role of insulin-like growth factor signaling in prostate cancer development and progression / Bruce Montgomery, James Dean, and Stephen Plymate -- IGF-1 cellular action and its relationship to cancer : evidence from in vitro and in vivo studies / Rosalyn D. Ferguson ... [et al.] -- Insulin-like growth factor signaling in pediatric sarcomas / Xiaolin Wan, Su Young Kim, and Lee J. Helman -- Cancer genes, tumor suppressors, and regulation of IGF1-R gene expression in cancer / Haim Werner ... [et al.] -- Mouse models of IGF-1R and cancer / Craig I. Campbell, James J. Petrik, and Roger A. Moorehead -- Targeting the insulin-like growth factor-I receptor in cancer therapy / David R. Clemmons -- Targeting insulin-like growth factor receptor 1 (IGF-1R) and insulin receptor signaling by tyrosine kinase inhibitors in cancer / Joan M. Carboni, Mark Wittman, and Fei Huang -- Calories and cancer : the role of insulin-like growth factor-1 / Stephen D. Hursting ... [et al.] -- Cancer cell metabolism / Akash Patnaik, Jason W. Locasale, and Lewis C. Cantley -- Overlaps between the insulin and IGF-I receptor and cancer / Antonino Belfiore and Roberta Malaguarnera.
650 0 $aSomatomedin.
650 0 $aInsulin-like growth factor-binding proteins.
650 0 $aCancer$xEndocrine aspects.
650 0 $aTumors$xGrowth.
650 12 $aSomatomedins.
650 22 $aInsulin-Like Growth Factor Binding Proteins.
650 22 $aNeoplasms.
700 1 $aLeRoith, Derek,$d1945-
830 0 $aCancer drug discovery and development.
856 42 $3Publisher description$uhttp://www.loc.gov/catdir/enhancements/fy1316/2011935731-d.html
856 41 $3Table of contents only$uhttp://www.loc.gov/catdir/enhancements/fy1316/2011935731-t.html