MARC record from Internet Archive

LEADER: 04566cam 2200673Mi 4500
001 ocn851378363
003 OCoLC
005 20210505144040.0
008 121227s1996 gw a ob 001 0 eng
006 m o d
007 cr mnu---uuaaa
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019 $a934992406$a936315583$a1012451838$a1016302128$a1058171304$a1086455249
020 $a9783642852084$q(electronic bk.)
020 $a3642852084$q(electronic bk.)
020 $a9783540593416
020 $a3540593411
020 $z9783642852107
020 $z3642852106
024 7 $a10.1007/978-3-642-85208-4$2doi
035 $a(OCoLC)851378363$z(OCoLC)934992406$z(OCoLC)936315583$z(OCoLC)1012451838$z(OCoLC)1016302128$z(OCoLC)1058171304$z(OCoLC)1086455249
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072 7 $aMJCM$2bicssc
072 7 $aMED044000$2bisacsh
072 7 $aMJCM$2thema
082 04 $a616.079$223
100 1 $aChisari, Francis V.
245 10 $aTransgenic Models of Human Viral and Immunological Disease /$cedited by Francis V. Chisari, Michael B.A. Oldstone.
260 $aBerlin, Heidelberg :$bSpringer Berlin Heidelberg,$c1996.
300 $a1 online resource (xi, 345 pages 53 illustrations)
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
347 $atext file$bPDF$2rda
490 1 $aCurrent Topics in Microbiology and Immunology,$x0070-217X ;$v206
520 $aMost diseases are multifactoral. Transgenic technology permits gene(s) of interest to be expressed in a small manipulatable laboratory animal model. By this process, murine models of human infections can be developed and studied; effects of cytokines in vivo, focally expressed in unique cells can be established and manipulated, and a variety of autoimmune disorders, mimicking human disease can be constructed. In this volume, these approaches for study of human immunodeficiency virus, hepatitis virus, viruses causing tumors and chronic degenerative disorders are described. Also included are chapters of transgenic models of autoimmune disorders like diabetes, systemic lupus and ankylosing spondylitis.
505 0 $aCytotoxic T Cell Effector and Memory Function in Viral Immunity -- Transgenic Mouse Models of Experimental Autoimmune Encephalomyelitis -- The Contribution of Insulitis to Diabetes Development in Tumor Necrosis Factor Transgenic Mice -- Influence of T Lymphocytes and Major Histocompatibility Complex Class II Genes on Diabetes Susceptibility in the NOD Mouse -- Virus-Induced Autoimmune Disease: Transgenic Approach to Mimic Insulin-Dependent Diabetes Mellitus and Multiple Sclerosis -- Role of HLA-B27 in Spondyloarthropathies -- The Influence of Cytokines on the Central Nervous System of Transgenic Mice -- Mx Transgenic Mice -- Animal Models of Health -- Hepatitis B Virus Transgenic Mice: Models of Viral Immunobiology and Pathogenesis -- Transgenic Models of HTLV-I Mediated Disease and Latency -- Transgenic Models of Human Immunodeficiency Virus Type-1 -- Transgenic Models in the Study of AIDS Dementia Complex -- Regulation of Expression and Pathogenic Potential of Human Foamy Virus In Vitro and in Transgenic Mice -- Transgenetics of Prion Diseases -- Poliovirus Biology and Pathogenesis -- Safety Requirements for Maintenance and Distribution of Transgenic Mice Susceptible to Human Viruses: The Example of Poliovirus-Susceptible Transgenic Mice.
504 $aIncludes bibliographical references at the end of each chapters and index.
546 $aEnglish.
650 0 $aMedicine.
650 0 $aImmunology.
650 0 $aNeurosciences.
650 0 $aCytology.
650 7 $aCytology.$2fast$0(OCoLC)fst00886282
650 7 $aImmunology.$2fast$0(OCoLC)fst00968006
650 7 $aMedicine.$2fast$0(OCoLC)fst01014893
650 7 $aNeurosciences.$2fast$0(OCoLC)fst01036509
655 4 $aElectronic books.
700 1 $aOldstone, Michael B. A.
776 08 $iPrint version:$z9783642852107
830 0 $aCurrent topics in microbiology and immunology ;$v206.
856 40 $3SpringerLink$uhttps://doi.org/10.1007/978-3-642-85208-4
856 40 $3SpringerLink$uhttps://link.springer.com/openurl?genre=book&isbn=978-3-540-59341-6
856 40 $3SpringerLink$uhttp://link.springer.com/10.1007/978-3-642-85208-4
029 0 $aAU@$b000051661898
029 1 $aNZ1$b15004694
029 1 $aNZ1$b15311411
994 $aZ0$bP4A
948 $hNO HOLDINGS IN P4A - 57 OTHER HOLDINGS