MARC record from Internet Archive

LEADER: 04763cam 2200805 a 4500
001 ocn233934347
003 OCoLC
005 20220719035044.0
008 081126s2009 nyu b 001 0 eng
010 $a 2008934289
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019 $a706076635
020 $a9781402089060$q(alk. paper)
020 $a1402089066$q(alk. paper)
020 $a9781402089077$q(e-ISBN)
020 $a1402089074$q(e-ISBN)
020 $a9789048180233$q(pbk.)
020 $a9048180236$q(pbk.)
035 $a(OCoLC)233934347$z(OCoLC)706076635
042 $anlmcopyc
050 4 $aR853.C55$bG38 2009
060 00 $a2008 N-762
060 10 $aW 20.5$bG265i 2009
082 04 $a610.72$222
100 1 $aGauch, Ronald R.
245 10 $aIt's great! oops, no it isn't :$bwhy clinical research can't guarantee the right medical answers /$cRonald R. Gauch.
246 30 $aWhy clinical research can't guarantee the right medical answers
260 $a[New York, N.Y.] :$bSpringer Science + Business Media,$c©2009.
300 $axiii, 298 pages ;$c25 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
504 $aIncludes bibliographical references (pages 255-281) and index.
505 0 $aPt. I, Medical research explained : -- Medical research: searching for answers -- The case-controlled method: looking backwards -- The cohort study: watchful waiting -- The clinical trial: the gold standard -- Comparing the methods: qualitative differences.
505 0 $aPt. II, Understanding the clinical trial : -- The protocol: the guiding light -- The control group: leveling the playing field -- Measurements: they're never exact -- Bias control: a closer look at blinding and randomization -- Utility: are clinical trial results useful? -- Research discrimination: inadequately tested populations -- Seven deadly flaws: the clinical trials' Achilles' heel.
505 0 $aPt. III, Tools of the trade : -- Statistics: was the funding significant? -- Analysis issues: a lot of choices -- Meta analysis: an alternative to large trials.
505 0 $aPt. IV, The real world : -- Research results that clashed: what's the right answer? -- Hormone replacement therapy: the silver bullet that misfired -- Publishing: getting the word out to doctors -- The public forum: sharing the news with the public -- Product development: getting discoveries to the market -- Medical innovations: regulators, resources, and results -- Science and politics: a troubling mixture -- Research misconduct; irresistible temptation -- Postmarketing surveillance: an imperfect system -- Regulatory reform: changes needed -- Journey's end: a call for action.
520 $a"This book dissects medical research methodology and through a penetrating inquiry into its triumphs and tragedies explains why correct answers are so hard to achieve. What emerges from this inquiry is the unexpected and stunning conclusion that medical researchers can never be sure that they've ended up with a truthful answer. In IT'S GREAT! readers learn why the quest for knowledge through clinical trials is fraught with problems that even the best researchers cannot overcome."--Jacket.
540 $aBritish Library not licensed to copy$c0.$5Uk
650 0 $aClinical medicine$xResearch$xMethodology.
650 0 $aClinical trials.
650 0 $aMedicine$xResearch$xMethodology.
650 12 $aBiomedical Research$xmethods
650 22 $aBias
650 22 $aClinical Trials as Topic$xmethods
650 22 $aResearch Design
650 22 $aStatistics as Topic$xmethods
650 2 $aClinical Trials as Topic
650 6 $aMédecine clinique$xRecherche$xMéthodologie.
650 6 $aÉtudes cliniques.
650 6 $aMédecine$xRecherche$xMéthodologie.
650 6 $aErreurs systématiques.
650 7 $aClinical medicine$xResearch$xMethodology.$2fast$0(OCoLC)fst00864381
650 7 $aClinical trials.$2fast$0(OCoLC)fst00864429
650 7 $aMedicine$xResearch$xMethodology.$2fast$0(OCoLC)fst01015079
655 4 $aFulltext.
655 4 $aInternet Resources.
938 $aBaker & Taylor$bBKTY$c59.95$d59.95$i1402089066$n0007863486$sactive
938 $aBaker and Taylor$bBTCP$nBK0007863486
938 $aYBP Library Services$bYANK$n2912496
938 $aYBP Library Services$bYANK$n3937658
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994 $aZ0$bIME
948 $hNO HOLDINGS IN IME - 76 OTHER HOLDINGS