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LEADER: 08480cam 2201165Ia 4500
001 ocn209910249
003 OCoLC
005 20200422193230.0
008 080226s2006 nyua ob 001 0 eng d
006 m o d
007 cr cn|||||||||
010 $a 2005934590
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020 $a9780387262833
020 $a0387262830
020 $a9780387262826$q(alk. paper)
020 $a0387262822$q(alk. paper)
020 $a6610616590
020 $a9786610616596
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037 $a978-0-387-26282-6$bSpringer$nhttp://www.springerlink.com
050 4 $aRC268.5$b.L53 2006eb
060 4 $aQZ 200 L756 2006
072 7 $aMED$x062000$2bisacsh
072 7 $aHEA$x039030$2bisacsh
082 04 $a616.99/4071$222
245 04 $aThe link between inflammation and cancer :$bwounds that do not heal /$cedited by Angus G. Dalgleish, Burkhard Haefner.
260 $aNew York :$bSpringer,$c℗♭2006.
300 $a1 online resource (xii, 254 pages) :$billustrations
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
490 1 $aCTAR ;$vv. 130
490 1 $aC.T.A.R. ;$v130
504 $aIncludes bibliographical references and index.
505 00 $tInflammation and cancer: the role of the immune response and angiogenesis /$rAngus G. Dalgleish and Ken O'Byrne --$tChronic inflammation and pathogenesis of GI and pancreatic cancers /$rLindsey N. Jackson and B. Mark Evers --$tCytokines, NF-[kappa]B, microenvironment, intestinal inflammation and cancer /$rArndt J. Schottelius and Harald Dinter --$tRegulation of NF-[kappa]B transcriptional activity /$rLinda Vermeulen, Wim Vanden Berghe and Guy Haegeman --$tThe role of immune cells in the tumor microenvironment /$rTheresa L. Whiteside--$tTumor-microenvironment interactions: the seletcin-selectin ligand axis in tumor-endothelium cross talk /$rIsaac P. Witz --$tCD95L/FasL and trail in tumour surveillance and cancer therapy /$rHarald Wajant --$tInfection & neoplastic growth 101: the required reading for microbial pathogens aspiring to cause cancer /$rJessica Berout and Andrei Thomas-Tikhonenko --$tCytokines as mediators and targets for cancer cachexia /$rJosep M. Argi e s, Si lvia Busquets and Francisco J. Lo pez-Soriano --$tTargeting NF-[kappa]B in anticancer adjunctive chemotherapy /$rBurkhard Haefner.
588 0 $aPrint version record.
520 $aThe transcription factor NF-kB has long been known to play a central role in the immune system by regulating the expression of key genes. Moreover, activation of this transcription factor helps a wide variety of cell types survive damage induced by pro-apoptotic stimuli. Owing to its critical role in the regulation of pro-inflammatory genes, NF-kB has long been regarded as a promising target for the discovery of anti-inflammatory drugs. More recently, NF-kB has emerged as a major culprit in a variety of human cancers mainly due to its ability to protect transformed cells from apoptosis. This finding should not have come as a surprise since there exists a link between inflammation and many types of cancer which was already suggested by Galen and later demonstrated by Virchow. This link, of crucial importance for the design of novel strategies for cancer treatment, is the topic of this book. Series Editor Cover Comments: "Inflammation is a known risk factor for a number of cancers. In this text, experts discuss the pathophysiology and molecular alterations that link these two processes. Potential therapeutics and preventive strategies are discussed." Steven T. Rosen, M.D. Series Editor.
650 0 $aCancer$xResearch.
650 0 $aChemokines.
650 0 $aInflammation.
650 2 $aNeoplasms.
650 2 $aNeoplasms$xetiology.
650 2 $aInflammation.
650 2 $aInflammation$xtherapy.
650 2 $aCytokines.
650 6 $aCancer$xRecherche.
650 6 $aChimiokines.
650 6 $aInflammation (Pathologie)
650 7 $aMEDICAL$xOncology.$2bisacsh
650 7 $aHEALTH & FITNESS$xDiseases$xCancer.$2bisacsh
650 7 $aCancer$xResearch.$2fast$0(OCoLC)fst00845497
650 7 $aChemokines.$2fast$0(OCoLC)fst00853583
650 7 $aInflammation.$2fast$0(OCoLC)fst00972432
653 00 $ageneeskunde
653 00 $amedicine
653 00 $avolksgezondheid
653 00 $apublic health
653 00 $aneoplasms
653 00 $aoncologie
653 00 $aoncology
653 10 $aMedicine (General)
653 10 $aGeneeskunde (algemeen)
655 4 $aElectronic books.
700 1 $aDalgleish, A. G.$q(Angus G.)
700 1 $aHaefner, Burkhard.
773 0 $tSpringer e-books
776 08 $iPrint version:$tLink between inflammation and cancer.$dNew York : Springer, ℗♭2006$z0387262822$z9780387262826$w(DLC) 2005934590$w(OCoLC)62866105
830 0 $aCancer treatment and research ;$v130.
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