Record ID | ia:molecularbiology0000unse_r5q8 |
Source | Internet Archive |
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LEADER: 06550cam 2200889Ia 4500
001 ocn162569064
003 OCoLC
005 20200515122453.0
008 070806s2004 ne a ob 001 0 eng d
006 m o d
007 cr cn|||||||||
040 $aOPELS$beng$epn$cOPELS$dOCLCG$dOCLCQ$dE7B$dOCLCQ$dOCLCO$dOCLCF$dOCLCQ$dOCLCO$dOCLCA$dUAB$dOCLCO$dOCLCA$dD6H$dOCLCO$dYDX$dOCLCO$dOCLCA$dLEAUB$dOCLCO$dOL$$dOCLCA
019 $a648257642$a989313970$a1055897792
020 $a9780120536412
020 $a0120536412
020 $a9780080479507
020 $a0080479502
035 $a(OCoLC)162569064$z(OCoLC)648257642$z(OCoLC)989313970$z(OCoLC)1055897792
037 $a97397:97398$bElsevier Science & Technology$nhttp://www.sciencedirect.com
050 4 $aQR185.6$b.M653 2004eb
060 4 $a2004 B-470
060 4 $aWH 200$bM7182 2004
082 04 $a616.07/98$222
084 $aWF 9880$2rvk
245 00 $aMolecular biology of B cells /$cedited by Tasuku Honjo, Frederick W. Alt, Michael S. Neuberger.
260 $aAmsterdam ;$aBoston :$bElsevier,$c2004.
300 $a1 online resource (xiv, 589 pages) :$bcolor illustrations
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
520 $aMolecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.
505 0 $aORGANIZATION, REARRANGEMENT AND TRANSCRIPTION OF IMMUNOGLOBULIN GENES -- Human Immunoglobulin heavy chains locus -- Immunoglobulin heavy chain genes of mouse -- Immunoglobulin? genes of human and mouse -- Immunoglobulin lambdav (IGL) genes of human and mouse -- The Mechanism of V(D) J Recombination -- Transcription of Immunoglobulin genes -- B CELLS AND THEIR DEVELOPMENT -- Early B cell development to a mature, antigen-sensitive cell -- cellular stages and molecular decisions -- Allelic exclusion, Isotypic exclusion and the Developmental Regulation of V(D)J Recombination -- The Development of Human B Lymphocytes -- Development and function of B cell subsets -- B CELL DIFFERENTIATION INDUCED BY Ag STIMULATION -- Structure and function of B cells antigen receptor complexes -- Regulation of antigen receptor signaling by the co-receptors, CD19 and CD22 -- The dynamic structure of antibody responses -- Dynamics of B cell migration to and within secondary lymphoid organs -- Characteristics of mucosal B cells with emphasis on the human secretory immune system -- The Cellular Basis of B Cell Memory -- Immunoglobulin assembly and secretion -- Fc And Complement Receptors -- Ig GENE ALTERATION IN PERIPHERY -- Regulation of Class Switch Recombination -- Molecular Mechanism of Class Switch Recombination -- Molecular Mechanism of Hypermutation -- Selection During Antigen-Driven B Cell Immune Responses: The Basis for High Affinity Antibody -- DISEASES OF B CELLS -- Chromosomal Translocations in B-cell Leukemias and Lymphomas -- Classification and Characteristics of Mouse B Cell-Lineage Lymphomas -- B cells producing pathogenic autoantibodies -- Immunodeficiencies Caused by B Cell Defects -- EVOLUTION OF Ig GENES -- Diverse forms of Immunoglobulin Genes in Lower Vertebrates -- Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Vertebrates: A Key Role for GALT -- The zebrafish immune system -- The Origin of V(D)J Diversification -- FUNCTION AND APPLICATION OF IMMUNOGLOBULINS -- Antibody Structure and Recognition of Antigen -- Monoclonal antibodies from display libraries -- Humanization of Monoclonal Antibodies -- Human monoclonal antibodies from translocus mice.
504 $aIncludes bibliographical references and index.
588 0 $aPrint version record.
650 0 $aMolecular immunology.
650 0 $aB cells.
650 0 $aImmunoglobulins.
650 0 $aImmunoglobulin genes.
650 6 $aImmunologie moléculaire.
650 6 $aLymphocytes B.
650 6 $aImmunoglobulines.
650 6 $aGènes de l'immunoglobuline.
650 7 $aB cells.$2fast$0(OCoLC)fst00824789
650 7 $aImmunoglobulin genes.$2fast$0(OCoLC)fst00967959
650 7 $aImmunoglobulins.$2fast$0(OCoLC)fst00967961
650 7 $aMolecular immunology.$2fast$0(OCoLC)fst01024811
650 7 $aLinfócitos b.$2larpcal
650 7 $aImunologia celular.$2larpcal
650 7 $aImunoglobulinas.$2larpcal
650 7 $aBiologia molecular.$2larpcal
650 7 $aB-Lymphozyt$2gnd
650 7 $aMolekularbiologie$2gnd
650 12 $aB-Lymphocytes$ximmunology.
650 22 $aGenes, Immunoglobulin.
650 22 $aGenetic Phenomena.
655 4 $aElectronic books.
655 0 $aElectronic books.
700 1 $aHonjo, T.$q(Tasuku),$d1942-
700 1 $aAlt, Frederick W.
700 1 $aNeuberger, M. S.$q(Michael S.)
776 08 $iPrint version:$tMolecular biology of B cells.$dAmsterdam ; Boston : Elsevier, 2004$z0120536412$z9780120536412$w(DLC) 2003064380$w(OCoLC)53970703
856 40 $3ebrary$uhttp://site.ebrary.com/id/10177019
856 40 $3Referex$uhttp://www.engineeringvillage.com/controller/servlet/OpenURL?genre=book&isbn=9780120536412$zAn electronic book accessible through the World Wide Web; click for information
856 40 $3ScienceDirect$uhttp://www.sciencedirect.com/science/book/9780120536412
856 41 $3Table of contents$uhttp://catdir.loc.gov/catdir/toc/els041/2003064380.html
856 42 $3Publisher description$uhttp://catdir.loc.gov/catdir/description/els041/2003064380.html
856 40 $3ScienceDirect$uhttp://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/book/9780120536412$zeBook available for Durham College via Elsevier. Click link to access
856 40 $3ScienceDirect$uhttps://ezproxy.aub.edu.lb/login?url=http://www.sciencedirect.com/science/book/9780120536412$zClick for electronic access to e-book.
938 $aebrary$bEBRY$nebr10177019
938 $aYBP Library Services$bYANK$n2613321
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029 1 $aDEBBG$bBV039830405
029 1 $aDEBSZ$b405306911
029 1 $aNZ1$b12434781
994 $aZ0$bP4A
948 $hNO HOLDINGS IN P4A - 180 OTHER HOLDINGS