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LEADER: 06956cam 2201225Ka 4500
001 ocn649863884
003 OCoLC
005 20200521235435.0
008 100723s1999 enka ob 001 0 eng d
006 m o d
007 cr un||a|a||||
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019 $a184983877$a288984071$a607461485$a647790681$a992885685$a995039943$a1064097817$a1081122955$a1100845525
020 $a9783527613656$q(electronic bk.)
020 $a352761365X$q(electronic bk.)
020 $a9783527613649
020 $a3527613641
020 $z3527300929
020 $z9783527300921
024 7 $a10.1002/9783527613649$2doi
035 $a(OCoLC)649863884$z(OCoLC)184983877$z(OCoLC)288984071$z(OCoLC)607461485$z(OCoLC)647790681$z(OCoLC)992885685$z(OCoLC)995039943$z(OCoLC)1064097817$z(OCoLC)1081122955$z(OCoLC)1100845525
037 $a10.1002/9783527613649$bWiley InterScience$nhttp://www3.interscience.wiley.com
042 $adlr
050 4 $aRM301.25$b.H65 1999
060 4 $a2000 E-877
060 4 $aQV 744$bH762n 1999
072 7 $aMED$x023000$2bisacsh
072 7 $aMED$x071000$2bisacsh
072 7 $aMED$x072000$2bisacsh
072 7 $aMED$x058170$2bisacsh
082 04 $a615.19$221
084 $aVG 9500$2rvk
084 $aCHE 808f$2stub
084 $aCHE 244f$2stub
084 $aCIT 840f$2stub
100 1 $aHolzgrabe, U.$q(Ulrike)
245 10 $aNMR spectroscopy in drug development and analysis /$cU. Holzgrabe, I. Wawer, B. Diehl.
260 $aWeinheim ;$aNew York ;$aChichester :$bWiley-VCH,$c©1999.
300 $a1 online resource (299 pages) :$billustrations
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
504 $aIncludes bibliographical references and index.
505 0 $aNMR spectroscopy in the European regulatory dossier / S. Branch -- Analysis of drugs / B.W.K. Diehl and U. Holzgrabe -- pH-dependent NMR measurements / G. Hägele and U. Holzgrabe -- Complexation behaviour of drugs studied by NMR / B.W.K. Diehl and U. Holzgrabe -- Determination of the isometric composition of drugs / B.W.K. Diehl and U. Holzgrabe -- On-line coupling of HPLC or SFC / K. Albert -- NMR of body fluids / U. Holzgrabe -- NMR as a tool in drug research / G. Gemmecker -- Ligand-cyclodextrin complexes / B. Chankvetadze, G. Blaschke and G. Pintore -- Ligand-membrane interaction / J.K. Seydel -- Solid-state NMR in drug analysis / I. Wawer -- MR imaging and MR spectroscopy / I. Wawer.
520 $aSince the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (& 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis. This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition o.
506 $3Use copy$fRestrictions unspecified$2star$5MiAaHDL
533 $aElectronic reproduction.$b[Place of publication not identified] :$cHathiTrust Digital Library,$d2010.$5MiAaHDL
538 $aMaster and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.$uhttp://purl.oclc.org/DLF/benchrepro0212$5MiAaHDL
583 1 $adigitized$c2010$hHathiTrust Digital Library$lcommitted to preserve$2pda$5MiAaHDL
588 0 $aPrint version record.
650 0 $aDrug development.
650 0 $aDrugs$xAnalysis.
650 0 $aNuclear magnetic resonance spectroscopy.
650 2 $aChemistry, Pharmaceutical.
650 2 $aDrug Design.
650 2 $aMagnetic Resonance Spectroscopy.
650 7 $aMEDICAL$xDrug Guides.$2bisacsh
650 7 $aMEDICAL$xPharmacology.$2bisacsh
650 7 $aMEDICAL$xPharmacy.$2bisacsh
650 7 $aMEDICAL$xNursing$xPharmacology.$2bisacsh
650 7 $aDrug development.$2fast$0(OCoLC)fst00898670
650 7 $aDrugs$xAnalysis.$2fast$0(OCoLC)fst00898769
650 7 $aNuclear magnetic resonance spectroscopy.$2fast$0(OCoLC)fst01040333
650 7 $aArzneimittelanalyse$2gnd
650 7 $aArzneimittelentwicklung$2gnd
650 7 $aNMR-Spektroskopie$2gnd
650 7 $aMédicaments$xAnalyse.$2ram
650 7 $aRésonance magnétique nucléaire.$2ram
650 7 $aSpectroscopie de la résonance magnétique nucléaire.$2ram
650 7 $aPharmacie$xRecherche.$2ram
650 07 $aArzneimittelanalyse.$2swd
650 07 $aArzneimittelentwicklung.$2swd
650 07 $aNMR-Spektroskopie.$2swd
655 4 $aElectronic books.
700 1 $aWawer, I.$q(Iwona)
700 1 $aDiehl, B.$q(Bernd)
776 08 $iPrint version:$aHolzgrabe, U. (Ulrike).$tNMR spectroscopy in drug development and analysis.$dWeinheim ; New York ; Chichester : Wiley-VCH, ©1999$w(OCoLC)42579355
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856 40 $3HathiTrust Digital Library, Limited view (search only)$uhttp://catalog.hathitrust.org/api/volumes/oclc/42579355.html
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856 40 $3Wiley$uhttps://doi.org/10.1002/9783527613649
856 40 $3Wiley$uhttps://onlinelibrary.wiley.com/doi/book/10.1002/9783527613649
856 40 $3Wiley$uhttp://catalogimages.wiley.com/images/db/jimages/9783527300921.jpg
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948 $hNO HOLDINGS IN P4A - 222 OTHER HOLDINGS