MARC record from Internet Archive

LEADER: 03197cam 2200373 i 4500
001 9925206298201661
005 20150624070343.1
008 140722t20152015maua b 001 0 eng
010 $a 2014028786
019 $a893899344
020 $a9781605353135
020 $a1605353132
035 $a99964354596
035 $a(OCoLC)884541397$z(OCoLC)893899344
035 $a(OCoLC)ocn884541397
040 $aDNLM/DLC$beng$erda$cDLC$dYDX$dNLM$dBTCTA$dYDXCP$dI3U$dOCLCF$dOCLCO
042 $apcc
050 00 $aRB155$b.G533 2015
082 00 $a616/.042$223
100 1 $aGibson, Greg,$d1963-$eauthor.
245 12 $aA primer of human genetics /$cGreg Gibson, Georgia Institute of Technology.
264 1 $aSunderland, Massachusetts, U.S.A. :$bSinauer Associates, Inc., Publishers,$c[2015]
264 4 $c℗♭2015
300 $axiii, 442 pages :$billustrations (chiefly color) ;$c24 cm
336 $atext$2rdacontent
337 $aunmediated$2rdamedia
338 $avolume$2rdacarrier
504 $aIncludes bibliographical references and index.
505 0 $aConceptual foundations -- The human genome -- Human evolution -- Normal variation -- Personalized genomics -- Genome-wide association studies -- Whole genome sequencing -- Gene expression profiling -- The epigenome -- Integrative genomics -- Immune-related diseases -- Metabolic diseases -- Cardiovascular diseases -- Cancer genetics -- Neurological and psychological disorders -- Genetics of aging.
520 $aA Primer of Human Genetics is an introductory textbook designed to give students the foundation they need to understand and appreciate the extraordinary shifts in human genetics that have accompanied the arrival of genomics. The book lays out the key concepts of human evolution, quantitative genetics, and personalized medicine before describing the tools that are missing from most contemporary textbooks: genome-wide association studies, whole-genome resequencing, gene expression and epigenome profiling, and integrative genomics. The final section provides an up-to-date survey of specific findings in six major domains of human disease: immunological, metabolic, cardiovascular, cancer, neuropsychological, and aging disorders. After reading this textbook, not only will students be better equipped to read current literature, they will gain a sense of the impact that the revolution in genomics has had for our understanding of the human condition, as well as of the major trends in human genetics research. Students are assumed to have a core understanding of genetics such as would be obtained in a general genetics class. Each chapter is approximately 20 pages long, and organized under up to ten sub-headings, most of which incorporate an illustrative figure. Chapter summary points recap the key messages, and references point students to key reviews and contemporary highlights. Several of the chapters contain a single box, which provides extra material on topics such as "Consent and Responsible Conduct of Research" and "Methylation Analysis in Biology."--Publisher description.
650 0 $aMedical genetics.
650 0 $aHuman genetics.
947 $hCIRCSTACKS$r31786103010408
980 $a99964354596