MARC record from Internet Archive

LEADER: 04816cam 2200673 4500
001 ocm00799619
003 OCoLC
005 20200522204208.0
008 731219s1974 nyua b 101 0 eng
007 ta
010 $a 73021823
040 $aDLC$beng$cDLC$dNLM$dOCL$dMUQ$dBTCTA$dOCLCG$dOCLCO$dOCLCF$dWUM$dOCLCQ$dOCLCO$dOCLCQ$dOCL$dEUW$dOCLCQ$dOKS$dOCLCQ$dOCLCO$dOCLCA$dU3G$dOCLCA
016 7 $a0412277$2DNLM
019 $a38248571$a367276145$a490307372$a978122688$a1086752738
020 $a0306390957$q(v. 1)
020 $a9780306390951$q(v. 1)
035 $a(OCoLC)799619$z(OCoLC)38248571$z(OCoLC)367276145$z(OCoLC)490307372$z(OCoLC)978122688$z(OCoLC)1086752738
050 00 $aQP801.P8$bI56 1973
060 00 $aW1$bAD559 v.41 1973
060 10 $aQU 58$bI635p 1973
082 00 $a612/.39
111 2 $aInternational Symposium on Purine Metabolism in Man$n(1st :$d1973 :$cTel Aviv, Israel)
245 10 $aPurine metabolism in man: enzymes and metabolic pathways;$b[proceedings]$cEdited by Oded Sperling and Andre De Vries and James B. Wyngaarden.
260 $aNew York,$bPlenum Press$c[1974]
300 $a2 volumes$billustrations$c26 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
338 $avolume$bnc$2rdacarrier
490 1 $aAdvances in experimental medicine and biology,$vv. 41
500 $aVol. 2 has subtitle: Biochemistry and pharmacology of uric acid metabolism.
504 $aIncludes bibliographical references.
505 0 $aContents. -- v. 1. Enzymes and metabolic pathways. -- v. 2. Biochemistry and pharmacology of uric acid metabolism.
520 $aGout and uric acid lithiasis are known to have affected mankind for thousands of years. It is only recently, however, that great progress has been made in the understanding of the processes involved in purine metabolism and its disorders in man. The key enzymes active in the various pathways of purine synthesis and degradation have become known and their properties are the subject of intensive study. Major contributions to the knowledge of normal purine metabolism in man have derived from the study of inborn errors in patients with purine disorders, specifically complete and partial hypoxanthine-guanine phosphoribosyltransferase deficiency. Mutations of other enzymes involved in purine metabolism are being discovered. A great step forward has been made in the treatment of gout with the introduction of uricosuric drugs and more recently of the hypoxanthine analogue allopurinol, a synthetic xanthine oxidase inhibitor. Furthermore, the complex nature of the renal handling of uric acid excretion, although still posing difficult problems, appears to approach clarification. In view of the intensive research on purine metabolism going on in various laboratories all over the world it was felt by several investigators in this field that the time was appropriate to convene a symposium dedicated to this subject. This book is the first of its kind, was therefore organized and held in Tel-Aviv, June 17 to 22, 1973. The meeting dealt with the various aspects of purine metabolism and its disorders - biochemistry, enzyme mutations, genetics, methodology, clinical aspects and treatment. This volume contains the full reports of all communications made at the symposium.
650 0 $aPurines$xMetabolism$vCongresses.
650 0 $aUric acid$xMetabolism$vCongresses.
650 2 $aPurine-Pyrimidine Metabolism, Inborn Errors.$0https://id.nlm.nih.gov/mesh/D011686
650 2 $aPurines$xmetabolism.$0https://id.nlm.nih.gov/mesh/D011687Q000378
650 6 $aPurines$xCongrès.
650 6 $aMétabolisme, Maladies héréditaires du$xCongrès.
650 6 $aPurines$xMétabolisme$xCongrès.
650 6 $aUrique, Acide$xMétabolisme$xCongrès.
650 7 $aPurines$xMetabolism.$2fast$0(OCoLC)fst01084344
650 7 $aUric acid$xMetabolism.$2fast$0(OCoLC)fst01162913
655 2 $aCongress.$0https://id.nlm.nih.gov/mesh/D016423
655 4 $aConference proceedings.
655 7 $aConference papers and proceedings.$2fast$0(OCoLC)fst01423772
700 1 $aSperling, Oded,$eeditor.
700 1 $aDe Vries, André,$d1911-$eeditor.
700 1 $aWyngaarden, James B.,$d1924-2019,$eeditor.
776 08 $iOnline version:$aInternational Symposium on Purine Metabolism in Man. (1st : 1973 : Tel Aviv, Israel).$tPurine metabolism in man: enzymes and metabolic pathways.$dNew York, Plenum Press [1974]$w(OCoLC)608626848
830 0 $aAdvances in experimental medicine and biology ;$vv. 41.
938 $aBaker and Taylor$bBTCP$n73021823
029 1 $aAU@$b000000724717
029 1 $aNLGGC$b781879965
029 1 $aNLM$b0412277
029 1 $aZWZ$b015733823
029 1 $aNZ1$b1465607
994 $aZ0$bP4A
948 $hNO HOLDINGS IN P4A - 231 OTHER HOLDINGS