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LEADER: 05655cam 2200781Ii 4500
001 ocn881633849
003 OCoLC
005 20200722084904.0
008 140623s1993 ne a ob 001 0 eng d
006 m o d
007 cr cnu---unuuu
040 $aOPELS$beng$erda$epn$cOPELS$dEBLCP$dOCLCQ$dYDXCP$dOCLCQ$dOCLCO$dNLE$dOCLCQ$dUKMGB$dOCLCQ
015 $aGBB807738$2bnb
016 7 $a018659094$2Uk
019 $a904207654
020 $a9781483290263$q(electronic bk.)
020 $a1483290263$q(electronic bk.)
020 $z0444814701
020 $z9780444814708
035 $a(OCoLC)881633849$z(OCoLC)904207654
037 $a9781483290263$bIngram Content Group
050 4 $aRC394.D35$bN48 1993eb
082 04 $a571.9/36$223
245 00 $aNeuronal cell death and repair /$cedited by A. Claudio Cuello.
264 1 $aAmsterdam :$bElsevier,$c1993.
300 $a1 online resource (xv, 317 pages) :$billustrations.
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
490 1 $aRestorative neurology,$x0169-0833 ;$vvolume 6
504 $aIncludes bibliographical references and index.
588 0 $aPrint version record.
505 0 $aFront Cover; Neuronal Cell Death and Repair; Copyright Page; List of Contributors; Preface; Table of Contents; SECTION I: Cellular and Molecular Mechanisms for Neuronal Cell Death; CHAPTER 1. An Introduction to Apoptosis; 1. Introduction; Acknowledgements; References; CHAPTER 2. Apoptosis; 1. Introduction; 2. Classical apoptosis; 3. Mechanisms of apoptosis and programmed cell death; 4. Apoptosis, differentiation and atrophy; 5. Conclusion; References; CHAPTER 3. Molecular mechanism of programmed cell death in the developing nervous system; 1. Introduction.
505 8 $a2. Control of neuronal death during development3. Molecular mechanism of neuronal death; 4. Regulation of trophic factor dependence; 5. Concluding comments; Acknowledgments; References; CHAPTER 4. Neurotrophic factors and apoptosis in the nervous system; 1. Developmental neuronal death in vertebrates as a stochastic process regulated by trophic factors; 2. Apoptosis as a possible mode of neuronal cell death; 3. Cultures of PC12 cells and sympathetic neurons as model systems to study neuronal cell death caused by withdrawal of neurotrophic factors.
505 8 $a4. Correlation of endonuclease activity with neuronal cell death caused by trophic factor deprivation5. Apoptotic neuronal death after insult; 6. Role of macromolecular synthesis in neuronal death and survival; 7. Signal transduction pathways mediating neuronal survival; 8. Summary, conclusions and further prospects; References; CHAPTER 5. The microtubule cytoskeleton in neuronal development and degeneration; 1. The MAP proteins in morphogenesis and neuronal degeneration; 2. The MAPI protein family; 3. The MAP2 Protein Family; 4. The function and dysfunction of the TAU protein family.
505 8 $a5. The significance of MAPs phosphorylation states in neuronal degenerationReferences; CHAPTER 6. Molecular biology and pathology of Alzheimer's disease; 1. Introduction; 2. The amyloid concept; 3. ß A4 amyloid protein in the aetiology of Alzheimer's disease; 4. The nature of the ""Alzheimer-specific"" ßA4 amyloid protein; 5. Synthetic ßA4 amyloid; 6. ßA4 amyloid protein deposition at synapses; 7. ßA4 protein as biological marker of preclinical Alzheimer's disease; 8. The family of ßA4 amyloid protein precursors (APP); 9. Processing of APP to ßA4; 10. Function of APP.
505 8 $a11. Regulation of the APP gene12. Mechanism and role of amyloid deposition in Alzheimer's disease; Acknowledgments; References; SECTION II: Chemically Induced Neuronal Cell Death; CHAPTER 7. Excitatory amino acids and free radicals in the genesis of ischemic neuronal death; 1. Introduction; 2. Free radicals release EAA; 3. A model of retina ischemia: possible actions of free radicals; 4. Thiokynurenates antagonize neuronal death by acting as NMDA antagonists and as inhibitors of lipoperoxidation.; Acknowledgements; References; CHAPTER 8. Cell death: a tough business; 1. Introduction.
520 $aNeuronal Cell Death and Repair.
650 0 $aNervous system$xDegeneration.
650 0 $aNervous system$xRegeneration.
650 0 $aCell death.
650 0 $aNeurons.
650 0 $aBrain$xCytology.
650 7 $aBrain$xCytology.$2fast$0(OCoLC)fst00837603
650 7 $aCell death.$2fast$0(OCoLC)fst00850180
650 7 $aNervous system$xDegeneration.$2fast$0(OCoLC)fst01036090
650 7 $aNervous system$xRegeneration.$2fast$0(OCoLC)fst01036139
650 7 $aNeurons.$2fast$0(OCoLC)fst01036436
650 17 $aNeuronen.$2gtt
650 17 $aRegeneratie.$2gtt
650 17 $aDegeneratie.$2gtt
650 7 $aNervenzelle$2gnd
650 7 $aRegenerationsfähigkeit$2gnd
655 4 $aElectronic books.
700 1 $aCuello, A. C.$q(A. Claudio),$eeditor.
776 08 $iPrint version:$tNeuronal cell death and repair$z0444814701$w(DLC) 93008095$w(OCoLC)28018451
830 0 $aRestorative neurology ;$vv. 6.
856 40 $3ScienceDirect$uhttp://www.sciencedirect.com/science/book/9780444814708
856 40 $uhttps://nls.ldls.org.uk/welcome.html?ark:/81055/vdc_100052724923.0x000001$zView item
938 $aProQuest Ebook Central$bEBLB$nEBL1926621
938 $aYBP Library Services$bYANK$n12233609
029 1 $aCHBIS$b010731585
029 1 $aCHVBK$b369207092
029 1 $aDEBBG$bBV042309641
029 1 $aGBVCP$b797021639
029 1 $aUKMGB$b018659094
994 $aZ0$bP4A
948 $hNO HOLDINGS IN P4A - 69 OTHER HOLDINGS