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LEADER: 08419aam a22008771i 4500
001 019064180
003 Uk
005 20180927022214.0
006 m || d |
007 cr |||||||||||
008 170918t20172017sz a ob 001 0 eng d
015 $aGBB8I4297$2bnb
020 $a9783319577326$q(electronic bk.)
020 $a3319577328$q(electronic bk.)
020 $z9783319577319$q(hardcover ;$qalk. paper)
020 $z331957731X$q(hardcover ;$qalk. paper)
024 7 $a10.1007/978-3-319-57732-6$2doi
037 $acom.springer.onix.9783319577326$bSpringer Nature
040 $aN$T$beng$cN$T$dMMU$dGW5XE$dEBLCP$dN$T$dYDX$dOTZ$dTFH$dAZU$dUPM$dMERER$dCASUM$dIOG$dCOO$dOCLCO$dOCLCQ$dOCLCO$dJG0$dOCLCO$dOCLCQ$dSNK$dOCLCO$dU3W$dOCLCO$dCAUOI$dOCLCQ$dOCLCO$dOCLCQ$dOCLCO$dKSU$dVT2$dOCLCO$dOCLCQ$dOCLCO$dUk$erda$epn
042 $aukblsr
050 4 $aQP535.C2
072 7 $aHEA$x039000$2bisacsh
072 7 $aMED$x014000$2bisacsh
072 7 $aMED$x022000$2bisacsh
072 7 $aMED$x112000$2bisacsh
072 7 $aMED$x045000$2bisacsh
072 7 $aPSF$2bicssc
082 04 $a616.804427$223
245 00 $aStore-operated Ca² entry (SOCE) pathways :$bemerging signaling concepts in human (patho)physiology /$cKlaus Groschner, Wolfgang F. Graier, Christoph Romanin, editors.
246 3 $aStore-operated calcium two plus entry (SOCE) pathways
246 3 $aSOCE pathways
264 1 $aCham, Switzerland :$bSpringer,$c[2017].
264 4 $c©2017
300 $a1 online resource (xxix, 645 pages) :$billustrations (chiefly color).
336 $atext$2rdacontent
337 $acomputer$2rdamedia
338 $aonline resource$2rdacarrier
490 1 $aAdvances in experimental medicine and biology,$x2214-8019 ;$vvolume 993
504 $aIncludes bibliographical references and index.
505 0 $aSOCE: fundamental mechanistic concepts. Introduction / James W. Putney -- The STIM-Orai pathway: STIM-Orai structures: isolated and in complex / Jinhui Zhu, Qingping Feng, Peter B. Stathopulos -- The STIM-Orai pathway: Orai, the pore-forming subunit of the CRAC channel / Aparna Gudlur, Patrick G. Hogan -- The STIM-Orai pathway: the interactions between STIM and Orai / Marc Fahrner, Rainer Schindl, Martin Muik, Isabella Derler, Christoph Romanin -- The STIM-Orai pathway: conformational coupling between STIM and Orai in the activation of store-operated Ca2+ entry / Robert M. Nwokonko, Xiangyu Cai, Natalia A. Loktionova, Youjun Wang, Yandong Zhou [and others] -- The STIM-Orai pathway: regulation of STIM and Orai by thiol modifications / Barbara A. Niemeyer -- The STIM-Orai pathway: light-operated Ca2+ entry through engineered CRAC channels / Guolin Ma, Shufan Wen, Yun Huang, Yubin Zhou -- STIM-TRPpathways and microdomain organization: Ca2+ influx channels: the Orai-STIM1-TRPC complexes / Dora Bodnar, Woo Young Chung, Dongki Yang, Jeong Hee Hong, Archana Jha, Shmuel Muallem -- STIM-TRP pathways and microdomain organization: contribution of TRPC1 in store-operated Ca2+ entry: impact on Ca2+ signaling and cell function / Hwei Ling Ong, Indu S. Ambudkar -- STIM-TRP pathways and microdomain organization: auxiliary proteins of the STIM/Orai complex / Jonathan Pacheco, Luis Vaca -- SOCE: crosstalk between organelle and cellular compartments. introduction / Alexei V. Tepikin -- New aspects of the contribution of ER to SOCE regulation: the role of the ER and ER-plasma membrane junctions in the regulation of SOCE / Hayley Dingsdale, Emmanuel Okeke, Lee Haynes, Gyorgy Lur, Alexei V. Tepikin -- New aspects of the contribution of ER to SOCE regulation: TRPC proteins as a link between plasma membrane ion transport and intracellular Ca2+ stores / Alexis Bavencoffe, Michael Xi Zhu, Jin-bin Tian -- The role of mitochondria in the activation/maintenance of SOCE: store-operated Ca2+ entry and mitochondria / András Spät, Gerg̲ Szanda -- The role of mitochondria in the activation/maintenance of SOCE: membrane contact sites as signaling hubs sustaining store-operated Ca2+ entry / Nicolas Demaurex, Daniele Guido -- The role of mitochondria in the activation/maintenance of SOCE: the contribution of mitochondrial Ca2+ uptake, mitochondrial motility, and location to store-operated Ca2+ entry / Roland Malli, Wolfgang F. Graier -- Tissue specificity: the role of organellar membrane nanojunctions in smooth muscle Ca2+ signaling / Nicola Fameli, A. Mark Evans, Cornelis van Breemen -- Tissue specificity: SOCE: implications for Ca2+ handling in endothelial cells / Lothar A. Blatter -- Tissue specificity: store-operated Ca2+ entry in cardiac myocytes / Martin D. Bootman, Katja Rietdorf -- SOCE: molecular and cellular (patho)physiology. Introduction: overview of the pathophysiological implications of store-operated calcium entry in mammalian cells / Juan A. Rosado -- Immunological disorders: regulation of Ca2+ signaling in T lymphocytes / Sonal Srikanth, Jin Seok Woo, Zuoming Sun, Yousang Gwack -- Cardiovascular and hemostatic disorders: role of STIM and Orai proteins in vascular disorders / Jyoti Tanwar, Mohamed Trebak, Rajender K. Motiani -- Cardiovascular and hemostatic disorders: SOCE and Ca2+ handling in platelet dysfunction / Jose J. Lopez, Gines M. Salido, Juan A. Rosado -- Cardiovascular and hemostatic disorders: SOCE in cardiovascular cells: emerging targets for therapeutic intervention / Klaus Groschner, Niroj Shrestha, Nicola Fameli -- Cardiac remodeling and disease: SOCE and TRPC signaling in cardiac pathology / Petra Eder -- Cardiac remodeling and disease: current understanding of STIM1/Orai1-mediated store-operated Ca2+ entry in cardiac function and pathology / Fiona Bartoli, Jessica Sabourin -- Neurological and motor disorders: neuronal store-operated Ca2+ signaling: an overview and its function / Sunitha Bollimuntha, Biswaranjan Pani, Brij B. Singh -- Neurological and motor disorders: TRPC in the skeletal muscle / Sophie Saüc, Maud Frieden -- Fertility: store-operated Ca2+ entry in germ cells: role in egg activation / Zoltan Machaty, Chunmin Wang, Kiho Lee, Lu Zhang -- Metabolic disorders and cancer: hepatocyte store-operated Ca2+ channels in nonalcoholic fatty liver disease / Eunüs S. Ali, Grigori Y. Rychkov, Greg J. Barritt -- Metabolic disorders and cancer: store-operated Ca2+ entry in cancer: focus on IP3R-mediated Ca2+ release from intracellular stores and its role in migration and invasion / Abigael Ritaine, George Shapovalov, Natalia Prevarskaya.
588 0 $aOnline resource; title from electronic title page (SpringerLink, viewed September 19, 2017).
650 0 $aLife sciences.
650 0 $aCalcium channels.
650 0 $aCellular signal transduction.
650 0 $aIntracellular calcium.
650 7 $aHEALTH & FITNESS$xDiseases$xGeneral.$2bisacsh
650 7 $aMEDICAL$xClinical Medicine.$2bisacsh
650 7 $aMEDICAL$xDiseases.$2bisacsh
650 7 $aMEDICAL$xEvidence-Based Medicine.$2bisacsh
650 7 $aMEDICAL$xInternal Medicine.$2bisacsh
650 7 $aCalcium channels.$2fast$0(OCoLC)fst00844063
650 7 $aCellular signal transduction.$2fast$0(OCoLC)fst00850288
650 7 $aIntracellular calcium.$2fast$0(OCoLC)fst01748758
650 12 $aCalcium Signaling.$0(DNLM)D020013.$0https://id.nlm.nih.gov/mesh/D020013
650 22 $aDisease$xgenetics.$0(DNLM)D004194Q000235.$0https://id.nlm.nih.gov/mesh/D004194Q000235
650 7 $aMedical$xBiochemistry.$2bisacsh
650 7 $aScience$xLife Sciences$xBiophysics.$2bisacsh
650 7 $aMedical$xCardiology.$2bisacsh
650 7 $aBiochemistry.$2bicssc
650 7 $aBiophysics.$2bicssc
650 7 $aCardiovascular medicine.$2bicssc
650 0 $aCytology.
650 0 $aBiochemistry.
650 0 $aCardiology.
650 7 $aScience$xLife Sciences$xBiology$xMolecular Biology.$2bisacsh
650 7 $aCellular biology (cytology).$2bicssc
655 4 $aElectronic books.
700 1 $aGroschner, Klaus,$eeditor.
700 1 $aGraier, Wolfgang F.,$eeditor.
700 1 $aRomanin, Christoph,$eeditor.
830 0 $aAdvances in experimental medicine and biology ;$vv. 993.$x0065-2598.
859 $aELD$bebook
884 $aLDL ebooks ONIX to marcxml transformation using Record_Load-eBooks_Legal_Deposit_onix2marc_v2-1.xsl$g20180924$kcom.springer.onix.9783319577326$qUk
889 $a(OCoLC)1004225472
852 $aBritish Library$bHMNTS$cDRT$jELD.DS.331271
903 $aELD.DS.331271