MARC record from Internet Archive

LEADER: 06287cam 22008774a 4500
001 ocm56105226
003 OCoLC
005 20180628222806.0
008 040806s2004 maua ob 001 0 eng d
006 m o d
007 cr cnu|unuuu||
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020 $a1402078560$q(electronic bk.)
020 $a9781402078569$q(electronic bk.)
020 $z9781402078088
020 $z1402078080
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050 4 $aRC280.S66$bT37 2004eb
060 4 $aW1$bCA693 v.120 2004
060 4 $aQZ 345$bT185 2004
072 7 $aMED$x062000$2bisacsh
072 7 $aHEA$x039030$2bisacsh
082 04 $a616.99/4$222
245 00 $aTargeting treatment of soft tissue sarcomas /$cedited by Jaap Verweij and Herbert M. Pinedo.
260 $aBoston :$bKluwer Academic Publishers,$c℗♭2004.
300 $a1 online resource (184 pages) :$billustrations.
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
347 $adata file$2rda
490 1 $aCTAR ;$vv. 120
490 1 $aC>T.A.R. ;$v120
504 $aIncludes bibliographical references and index.
505 0 $a1. Targeted therapy : ready for prime time? / C. Seynaeve and J. Verweij -- 2. Volume-based radiotherapy targeting in soft tissue sarcoma / Iain Ward [and others] -- 3. Preoperative therapy for soft tissue sarcoma / Janice N. Cormier, Howard N. Langstein, Peter W.T. Pisters -- 4. TNF-based isolated limb perfusion : a decade of experience with antivascular therapy in the management of locally advanced extremity soft tissue sarcomas / Dirk J Grunhagen [and others] -- 5. Pitfalls in pathology of soft tissue sarcomas / Judith V.M.G. Bovee and Pancras C.W. Hogendoorn -- 6. Molecular biology and cytogenetics of soft tissue sarcomas : relevance for targeted therapies / Jonathan Fletcher -- 7. KIT and PDGF as targets / Jaap Verweij -- 8. Targeting mutant kinases in gastrointestinal stromal tumors : a paradigm for molecular therapy of other sarcomas / Mike C. Heinrich, Christopher L. Corless -- 9. Targeting other abnormal signalling pathways in sarcoma : EGFR in synovial sarcomas, PPAR-y in liposarcoma / Jean-Yves Blay [and others] -- 10. Angiogenesis : a potential target for therapy of soft tissue sarcomas / K. Hoekman and H.M. Pinedo.
520 $aRecent achievements in the development of new techniques and agents for the treatment of cancer in general as well as for soft tissue sarcomas are tremendous. Molecular biology research has changed the landscape considerably and an increasing number of subtypes of soft tissue sarcomas are related to changes in cellular growth factors in the cell signaling pathways. This enables the development of targeted agents with specific activity against these factors. The presence of the KIT receptor at the surface of the gastrointestinal stroma tumor cell, and the activation constituted by mutations has.
588 0 $aPrint version record.
650 0 $aSoft tissue tumors$xTreatment.
650 0 $aSarcoma$xTreatment.
650 0 $aDrug targeting.
650 7 $aMEDICAL$xOncology.$2bisacsh
650 7 $aHEALTH & FITNESS$xDiseases$xCancer.$2bisacsh
650 7 $aDrug targeting.$2fast$0(OCoLC)fst00898709
650 7 $aSarcoma$xTreatment.$2fast$0(OCoLC)fst01105480
650 2 $aSarcoma$xtherapy.
650 2 $aAntineoplastic Agents.
650 2 $aDrug Delivery Systems$xmethods.
650 2 $aGrowth Substances.
650 2 $aReceptors, Growth Factor.
650 2 $aSarcoma$xphysiopathology.
655 4 $aElectronic books.
700 1 $aVerweij, J.$q(Jaap)
700 1 $aPinedo, H. M.
776 08 $iPrint version:$tTargeting treatment of soft tissue sarcomas.$dBoston : Kluwer Academic Publishers, ℗♭2004$z1402078080$w(DLC) 2004044222$w(OCoLC)54501470
830 0 $aCancer treatment and research ;$v120.
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856 40 $3SpringerLink$uhttp://dx.doi.org/10.1007/b113259
856 40 $3SpringerLink$uhttp://link.springer.com/10.1007/b113259
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856 40 $zClick for electronic text$uhttp://uiwtx.idm.oclc.org/login?url=http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=114042
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856 40 $uhttps://login.lacollegelibrary.idm.oclc.org/login?url=http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=114042
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