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LEADER: 02572cam a22003977a 4500
001 2007933147
003 DLC
005 20080311120559.0
008 070717s2007 njua b 001 0 eng
010 $a 2007933147
015 $aGBA729011$2bnb
016 7 $a013716106$2Uk
020 $a9781588296832 (hbk. : alk. paper)
020 $a1588296830 (hbk. : alk. paper)
035 $a(OCoLC)ocn123375303
040 $aUKM$cUKM$dYDX$dBTCTA$dYDXCP$dVAM$dPIT$dGUA$dCOU$dCLU$dOCLCQ$dDLC
042 $alccopycat
050 00 $aQP606.T44$bA537 2007
082 04 $a612.015192$222
100 1 $aAndrews, Lucy G.
245 10 $aTelomerase inhibition :$bstrategies and protocols /$cedited by Lucy G. Andrews and Trygve O. Tollefsbol.
260 $aTotowa, N.J. :$bHumana,$cc2007.
300 $ax, 193 p. :$bill. ;$c24 cm.
490 1 $aMethods in molecular biology ;$v405
504 $aIncludes bibliographical references and index.
505 0 $aMethods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect.
650 0 $aTelomerase$xInhibitors.
650 0 $aTelomerase$vLaboratory manuals.
650 2 $aTelomerase$xantagonists & inhibitors
650 2 $aUrinary Bladder Neoplasms$xdrug therapy
650 2 $aDrug Therapy
650 2 $aOligonucleotides
700 1 $aTollefsbol, Trygve O.
830 0 $aMethods in molecular biology (Clifton, N.J.) ;$v405
856 42 $3Publisher description$uhttp://www.loc.gov/catdir/enhancements/fy0825/2007933147-d.html
856 41 $3Table of contents only$uhttp://www.loc.gov/catdir/enhancements/fy0825/2007933147-t.html