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LEADER: 07256cam 2201045Ka 4500
001 ocn624398404
003 OCoLC
005 20200519020055.0
008 100521s1993 ne ob 001 0 eng d
006 m o d
007 cr bn||||abp||
007 cr bn||||ada||
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019 $a646575995$a893741762$a987675182$a1100942839
020 $a9781483193229$q(electronic bk.)
020 $a1483193225$q(electronic bk.)
020 $z0444814825$q(acid-free paper)
020 $z9780444814821$q(acid-free paper)
035 $a(OCoLC)624398404$z(OCoLC)646575995$z(OCoLC)893741762$z(OCoLC)987675182$z(OCoLC)1100942839
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050 4 $aRG627.6.C45$bT47 1993
060 4 $a1994 C-192
060 4 $aQS 679$bT315 1993
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245 00 $aTeratogens :$bchemicals which cause birth defects /$cedited by Vera M. Kolb.
250 $a2nd completely rev. ed.
260 $aAmsterdam ;$aNew York :$bElsevier Science Publishers,$c℗♭1993.
300 $a1 online resource (vii, 586 pages)
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
504 $aIncludes bibliographical references and index.
506 $3Use copy$fRestrictions unspecified$2star$5MiAaHDL
533 $aElectronic reproduction.$b[S.l.] :$cHathiTrust Digital Library,$d2010.$5MiAaHDL
538 $aMaster and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.$uhttp://purl.oclc.org/DLF/benchrepro0212$5MiAaHDL
583 1 $adigitized$c2010$hHathiTrust Digital Library$lcommitted to preserve$2pda$5MiAaHDL
588 0 $aPrint version record.
505 0 $aFront Cover; Teratogens Chemicals which Cause Birth Defects; Copyright Page; PREFACE; Table of Contents; Chapter 1. PRINCIPLES AND MECHANISMS OF TERATOGENESIS; 1. HISTORICAL ASPECTS; 2. DEFINITIONS; 3. GENERAL PRINCIPLES OF TERATOLOGY; 4. INITIATING MECHANISMS OF TERATOGENESIS; 5. HUMAN TERATOGENS: EXAMPLES AND TYPES OF EFFECTS; 6. ROLE OF BIOACTIVATION IN TERATOGENESIS; 7. CONCLUSIONS; REFERENCES; Chapter 2. Maternal occupational exposure and spontaneous abortion; INTRODUCTION; EPIDEMIOLOGY OF SPONTANEOUS ABORTION.
505 8 $aSOME MECHANISMS FOR THE EFFECTS OF ENVIRONMENTALEXPOSURE ON THE OUTCOME OF PREGNANCYOCCUPATIONAL EXPOSURE AND SPONTANEOUS ABORTION; CONCLUSIONS; ACKNOWLEDGMENTS; REFERENCES; Chapter 3. BIOCHEMICAL DETERMINANTS OF CHEMICAL TERATOGENESIS: STUDIES WITH PHENYTOIN, BENZO(A)PYRENE AND RELATED XENOBIOTICS; REACTIVE INTERMEDIATES; TERATOGENICITY OF PHENYTOIN AND STRUCTURALLY RELATEDXENOBIOTICS; UDP-GLUCURONOSYLTRANSFERASES (UGTs) AND BENZO(A)PYRENE TERATOGENESIS; SUMMARY; ACKNOWLEDGEMENTS; REFERENCES; Chapter 4. LEGAL AND ETHICAL ASPECTS OF FETAL PROTECTION POLICIES; EQUAL EMPLOYMENT OPPORTUNITY.
505 8 $aEEO AND FETAL PROTECTION POLICIESIMPLICATIONS FOR EMPLOYERS; REFERENCES; Chapter 5. TERATOGENIC CHEMICALS IN UNDERGRADUATE CHEMISTRY LABORATORIES; 1. WHAT SUBSTANCES ARE PRESENT IN UNDERGRADUATE LABORATORIES?; 2. WHICH COMPOUNDS ARE TERATOGENIC?; 3. POTENTIAL TERATOGENS IN CHEMISTRY LABORATORY MANUALS; 4. TYPES OF TERATOGENS; 5. THE UNIQUE HAZARDS OF TERATOGENS; 6. THE MICROSCALE LABORATORY; 7. CONCLUSION; REFERENCES; Chapter 6. HOW TO OBTAIN INFORMATION ABOUT THE TERATOGENIC POTENTIAL OFCHEMICALS; INTRODUCTION; THE LITERATURE OF TERATOLOGY.
505 8 $aDATABASES SPECIALIZING IN TERATOLOGY AND DEVELOPMENTAL/REPRODUCTIVE TOXICITY INFORMATIONCONCLUSION; ACKNOWLEDGEMENTS; REFERENCES; Chapter 7. REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES AS A SOURCE FOR COMPILING A LIST OF TERATOGENS; REFERENCES; LIST OF CHEMICALS FROM RTECs WHICH CAUSE REPRODUCTIVE EFFECTS; Chapter 8. SAFE HANDLING OF TERATOGENIC CHEMICALS IN THE LABORATORY; NEW DEVELOPMENTS; LITERATURE; CONCLUSION; REFERENCES; SUBJECT INDEX.
520 $aTeratogens Chemicals Which Cause Birth Defects, 2nd Revised Edition is a collection of papers that discusses the practical aspect of teratogens, particularly regarding information on the teratogenic potential of chemicals. This book describes the principles and mechanism of teratogenesis, including the initiating mechanisms during the subcellular or molecular level and the role of bio-activation in teratogenesis. Investigations have been done on the relationship between spontaneous abortion in women exposed to organic solvents, antineoplastic agents, and chemicals in plastics. Other studies a.
650 0 $aFetus$xEffect of chemicals on.
650 0 $aAbnormalities, Human$xEtiology.
650 0 $aTeratogenic agents.
650 6 $aF¿tus, Effets des produits chimiques sur le.
650 6 $aMalformations$xE tiologie.
650 6 $aAgents te ratoge nes.
650 7 $aHEALTH & FITNESS$xDiseases$xGeneral.$2bisacsh
650 7 $aMEDICAL$xClinical Medicine.$2bisacsh
650 7 $aMEDICAL$xDiseases.$2bisacsh
650 7 $aMEDICAL$xEvidence-Based Medicine.$2bisacsh
650 7 $aMEDICAL$xInternal Medicine.$2bisacsh
650 7 $aAbnormalities, Human$xEtiology.$2fast$0(OCoLC)fst00794458
650 7 $aFetus$xEffect of chemicals on.$2fast$0(OCoLC)fst00923446
650 7 $aTeratogenic agents.$2fast$0(OCoLC)fst01147799
650 17 $aAangeboren afwijkingen.$2gtt
650 17 $aChemische stoffen.$2gtt
650 7 $aTeratogen$2gnd
650 12 $aTeratogens.
653 0 $aHumans$aCongenital disorders$aCauses$aChemicals
655 4 $aElectronic books.
700 1 $aKolb, Vera M.
776 08 $iPrint version:$tTeratogens.$b2nd completely rev. ed.$dAmsterdam ; New York : Elsevier Science Publishers, ℗♭1993$w(DLC) 93025703$w(OCoLC)28418225
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