MARC record from Internet Archive

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020 $a9783319143408$q(electronic bk.)
020 $a3319143409$q(electronic bk.)
020 $a3319143395
020 $a9783319143392
020 $z9783319143392
024 7 $a10.1007/978-3-319-14340-8$2doi
035 $a(OCoLC)903644033$z(OCoLC)908041881$z(OCoLC)1005807726$z(OCoLC)1011951688$z(OCoLC)1022015082$z(OCoLC)1026461033$z(OCoLC)1048186889$z(OCoLC)1066579704$z(OCoLC)1110862087$z(OCoLC)1112538097$z(OCoLC)1119469771$z(OCoLC)1127171295$z(OCoLC)1162755419
037 $acom.springer.onix.9783319143408$bSpringer Nature
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100 1 $aRobert, Jacques,$d1949-$eauthor.
245 10 $aTextbook of cell signalling in cancer :$ban educational approach /$cJacques Robert.
264 1 $aCham :$bSpringer,$c2015.
300 $a1 online resource (xxiii, 328 pages) :$billustrations (some color)
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
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500 $a"Updated translation from the French language edition "Signalisation cellulaire et cancer" by J. Robert ©Springer-Verlag France, Paris, 2010."
504 $aIncludes bibliographical references.
588 0 $aOnline resource; title from PDF title page (SpringerLink, viewed February 25, 2015).
520 $aThis book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis. This comprehensive reference text is based on the masterℓ́ℓs courses delivered by Prof. Jacques Robert to graduate students at the University of Bordeaux, France. It includes a large number of colour schemas and figures that have been improved year after year for educational purposes. Signalling pathways are described individually and in depth, but without ignoring the multiplicity of interconnections and crosstalk. The presentation of each pathway is followed by a brief description of the alterations found in cancers as well as of the targeted pharmacological approaches that can be used to prevent or overcome the consequences of these oncogenic alterations. The basic mechanisms of molecular biology at the DNA replication, RNA transcription and protein activity levels are presented in a series of didactic annexes, enabling readers to better understand the alterations in signalling pathways.
505 0 $aGrowth Factors and Tyrosine Kinase Receptors -- MAP Kinases Pathway -- Phosphatidylinositol 3-Kinase Pathway -- Cytokine Pathway -- TGF? Pathway -- G-proteins-coupled Receptors -- Wnt Pathway -- Notch Pathway -- Hedgehog Pathway -- Integrins -- Semaphorins and Adhesion Molecules -- Toll-like Receptors, Interleukin 1 (IL1) and NF?B -- Lymphocyte Receptors Pathways -- Nuclear Receptors Pathways -- Ion Channels-coupled Receptors -- Signalling by Oxygen and Nitric Oxide -- Cell Cycle Control -- Apoptosis Induction and Regulation.
546 $aEnglish.
650 0 $aCarcinogenesis.
650 0 $aCellular signal transduction.
650 0 $aCancer$xMolecular aspects.
650 2 $aNeoplastic Processes$xphysiopathology
650 2 $aReceptors, Cell Surface$xphysiology
650 2 $aSignal Transduction$xphysiology
650 2 $aNeoplasms$xphysiopathology
650 2 $aSignal Transduction
650 14 $aBiomedicine.
650 24 $aCancer Research.
650 24 $aOncology.
650 24 $aMolecular Medicine.
650 24 $aPharmacology/Toxicology.
650 24 $aCell Biology.
650 6 $aCancérogenèse.
650 6 $aTransduction du signal cellulaire.
650 6 $aCancer$xAspect moléculaire.
650 7 $aOncology.$2bicssc
650 7 $aMedical research.$2bicssc
650 7 $aPharmacology.$2bicssc
650 7 $aCellular biology (cytology)$2bicssc
650 7 $aSCIENCE$xLife Sciences$xAnatomy & Physiology.$2bisacsh
650 7 $aCancer$xMolecular aspects.$2fast$0(OCoLC)fst00845397
650 7 $aCarcinogenesis.$2fast$0(OCoLC)fst00846974
650 7 $aCellular signal transduction.$2fast$0(OCoLC)fst00850288
653 00 $ageneeskunde
653 00 $amedicine
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653 00 $apharmacology
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653 00 $atoxicology
653 00 $acelbiologie
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653 00 $abiomedische wetenschappen
653 00 $abiomedicine
653 00 $aneoplasms
653 00 $aoncologie
653 00 $aoncology
653 10 $aMedicine (General)
653 10 $aGeneeskunde (algemeen)
655 0 $aElectronic books.
655 4 $aElectronic books.
776 08 $iPrinted edition:$z9783319143392
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856 40 $3SpringerLink$uhttps://doi.org/10.1007/978-3-319-14340-8
856 40 $3SpringerLink$uhttps://link.springer.com/book/10.1007/978-3-319-14339-2
856 40 $3SpringerLink$uhttps://link.springer.com/book/10.1007/978-3-319-14340-8
856 4 $3Cover$uhttp://swbplus.bsz-bw.de/bsz433950536cov.htm$v20150618172756
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856 40 $uhttp://dx.doi.org/10.1007/978-3-319-14340-8$zAn electronic book accessible through the World Wide Web; click to view
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856 40 $uhttps://link.springer.com/10.1007/978-3-319-14340-8
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