MARC record from Internet Archive

LEADER: 04665cam a2200481 a 4500
001 2012405266
003 DLC
005 20120712090138.0
008 120517s2010 dcuab b 100 0 eng c
010 $a 2012405266
016 7 $a101551948$2DNLM
016 7 $a015768336$2Uk
020 $a9780309153324
020 $a0309153328
035 $a(OCoLC)ocn658581476
040 $aNLM$beng$cNLM$dYDXCP$dNRZ$dUPM$dUBY$dCDX$dUKMGB$dOCLCQ$dDLC
042 $apcc
043 $an-us---
050 00 $aR853.C55$bT73 2010
082 00 $a610.72/4$223
060 00 $a2011 A-819
060 10 $aQV 771
245 00 $aTransforming clinical research in the United States :$bchallenges and opportunities : workshop summary /$cRebecca A. English, Yeanwoo Lebovitz, and Robert B. Giffin, rapporteurs ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies.
260 $aWashington, D.C. :$bNational Academies Press,$cc2010.
300 $axvii, 131 p. :$bill. (some col.), col. maps ;$c23 cm.
504 $aIncludes bibliographical references (p. 103-105).
505 0 $aIntroduction -- The state of clinical research in the United States: an overview -- Challenges in clinical research -- Clinical trials in cardiovascular disease -- Clinical trials in depression -- Clinical trials in cancer -- Clinical trials in diabetes -- Building a robust clinical trials infrastructure.
520 $a"An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise."--Publisher's description.
530 $aAlso available online.
650 0 $aClinical trials$zUnited States$vCongresses.
650 0 $aClinical trials$xResearch$zUnited States$vCongresses.
650 0 $aClinical trials$xGovernment policy$zUnited States$vCongresses.
650 12 $aClinical Trials as Topic$zUnited States$vCongresses.
650 22 $aDrug Discovery$zUnited States$vCongresses.
650 22 $aPublic Policy$zUnited States$vCongresses.
700 1 $aEnglish, Rebecca A.
700 1 $aLebovitz, Yeonwoo.
700 1 $aGiffin, Robert B.
710 2 $aInstitute of Medicine (U.S.).$bForum on Drug Discovery, Development, and Translation.
710 2 $aNational Academies Press (U.S.)
856 4 $uhttp://www.ncbi.nlm.nih.gov/books/NBK50892
856 41 $3National Academies Press$uhttp://www.nap.edu/catalog.php?record_id=12900
856 41 $uhttp://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=nap12900