| Record ID | marc_columbia/Columbia-extract-20221130-003.mrc:438003563:3734 |
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LEADER: 03734fam a2200373 a 4500
001 1478440
005 20220602043441.0
008 930720t19941994enka b 001 0 eng
010 $a 93030023
020 $a0471941549
035 $a(OCoLC)28633094
035 $a(OCoLC)ocm28633094
035 $9AJA1492CU
035 $a(NNC)1478440
035 $a1478440
040 $aDLC$cDLC$dDLC
050 00 $aQP517.C45$bR44 1994
082 00 $a574.87/6$220
245 00 $aRegulation of cellular signal transduction pathways by densensitization [i.e. desensitization] and amplification /$cedited by David R. Sibley and Miles D. Houslay.
260 $aChichester ;$aNew York :$bJ. Wiley,$c[1994], ©1994.
300 $aix, 368 pages :$billustrations ;$c24 cm.
336 $atext$2rdacontent
337 $aunmediated$2rdamedia
338 $avolume$2rdacarrier
490 1 $aWiley series on molecular pharmacology of cell regulation ;$vv. 3
504 $aIncludes bibliographical references and index.
505 0 $aPt. I. Sensory Transduction Systems. 1. Adaptive Responses in Bacterial Chemotaxis / J. B. Stock. 2. Regulation of Visual Transduction / P. A. Hargrave and H. E. Hamm -- Pt. II. G-Protein-Linked Receptors. 3. Adrenergic Receptor-coupled Adenylyl Cyclase Systems: Regulation of Receptor Function by Phosphorylation, Sequestration and Downregulation / S. B. Liggett and R. J. Lefkowitz. 4. Genetic (Transcriptional and Post-transcriptional) Regulation of G-protein-linked Receptor Expression / S. Bahouth and C. C. Malbon. 5. Desensitization of Muscarinic Cholinergic Receptors and the Role of Protein Phosphorylation / M. M. Hosey. 6. Protein Kinase C and the Modulation of G-protein-controlled Adenylyl Cyclase and Other Signal Transmission Systems / M. D. Houslay. 7. Regulation of Phosphoinositidase C-linked Receptors and Phosphinositide-mediated Cell Signalling / R. J. H. Wojcikiewicz, A. B. Tobin, S. T. Safrany and S. R. Nahorski -- Pt. III. G-Protein Regulation.
505 0 $a8. Sensitization of Adenylyl Cyclase by Prior Activation of Inhibitory Receptors / J. M. Thomas and B. B. Hoffman. 9. Adenosine Receptor/Adenylyl Cyclase Modulation: Heterologous Regulation at the G-protein Level / V. Ramkumar and G. L. Stiles. 10. Receptor-mediated Downregulation of Cellular G-protein Levels as a Mechanism for the Development of Sustained Heterologous Densensitization / G. Milligan and A. Green -- Pt. IV. Peptide Receptors/Tyrosine Kinases. 11. Regulation of Insulin Receptor Function by Phosphorylation / C. M. Anderson and J. M. Olefsky. 12. Regulation of the Epidermal Growth Factor Receptor by Phosphorylation / K. A. Lund and H. S. Wiley -- Pt. V. Ion Channels. 13. Ligand-gated Ion Channels: Molecular Structure and Functional Regulation by Phosphorylation / M. D. Browning and S. W. Rogers. 14. Modulation of Sodium and Calcium Channels by Protein Phosphorylation / W. A. Catterall.
520 $aAmplification and desensitization are well recognized phenomena in signal transduction systems and descriptions of such phenomena are essential in order to gain insight into the coordinated functioning of cells in normal, pathological and transformed states. Written by international experts, this book will appeal to biochemists, pharmacologists and other experimental biologists interested in cellular signalling systems.
650 0 $aCellular signal transduction.$0http://id.loc.gov/authorities/subjects/sh89002397
700 1 $aSibley, David Robert,$d1954-$0http://id.loc.gov/authorities/names/n88639658
700 1 $aHousley, Miles D.
830 0 $aWiley series on molecular pharmacology of cell regulation ;$vv. 3.$0http://id.loc.gov/authorities/names/n88540475
852 00 $boff,bio$hQP517.C45$iR44 1994