MARC Record from marc_columbia

LEADER: 03059fam a2200397 a 4500
001 1609345
005 20220608195736.0
008 940519s1995 nyua b 001 0 eng
010 $a 94025809
020 $a0195091507
035 $a(OCoLC)30594535
035 $a(OCoLC)ocm30594535
035 $9AKL5878CU
035 $a(NNC)1609345
035 $a1609345
040 $aDLC$cDLC$dNNC$dOrLoB
050 00 $aTP248.65.I49$bA57 1994
082 00 $a616.07/93$220
245 00 $aAntibody engineering /$cedited by Carl A.K. Borrebaeck.
250 $a2nd ed.
260 $aNew York :$bOxford University Press,$c1995.
263 $a9407
300 $axv, 390 pages :$billustrations ;$c24 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
490 1 $aBreakthroughs in molecular biology
504 $aIncludes bibliographical references and index.
505 0 $a1. Antibody Structure and Function -- 2. Human Monoclonal Antibodies from V-Gene Repertoires Expressed on Bacteriophage -- 3. Synthetic Antibodies -- 4. Engineering the Antibody Combining Site by Codon-Based Mutagenesis in a Filamentous Phage Display System -- 5. Human Metaphoric Antibodies from a Phagemid Library -- 6. Stragies for Humanizing Antibodies -- 7. Single-Chain Fv Design and Production by Preparative Folding -- 8. Expressing Antibodies in Escherichia Coli -- 9. Vectors and Approaches for the Eukaryotic Expression of Antibodies and Antibody Fusion Proteins -- 10. The Cloning of Hybridoma V Regions for Their Ectopic Expression in Intracellular and Intercellular Immunization -- 11. The Expression of "Single Chain" Antibodies in Transgenic Plants.
520 $aAs the field of antibody engineering continues its explosive growth, more and more scientists around the world are striving to keep up with the latest developments. Now in its second edition, Antibody Engineering is the perfect one-stop introduction to state-of-the-art technologies emerging in the field today.
520 8 $aIn presenting a practical overview of the engineering of recombinant human or mouse monoclonal antibodies, the book incisively addresses essential topics such as antibody structure relevant to engineering, recombinatorial cDNA libraries, phage display, synthetic and humanized antibodies, engineering of affinity and biological effector functions, and plant, mammalian, and bacterial expression vectors and hosts. Antibody Engineering, Second Edition - written by leading experts and now thoroughly updated - is a unique resource for current information on the subject.
520 8 $aIt will be welcomed by researchers in immunology, biotechnology, molecular biology, and biochemistry.
650 0 $aImmunoglobulins$xBiotechnology.$0http://id.loc.gov/authorities/subjects/sh2010002784
650 0 $aProtein engineering.$0http://id.loc.gov/authorities/subjects/sh86007375
700 1 $aBorrebaeck, Carl A. K.,$d1948-$0http://id.loc.gov/authorities/names/n87842879
830 0 $aBreakthroughs in molecular biology.
852 00 $boff,eng$hTP248.65.I49$iA57 1994