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LEADER: 04302mam a22003735a 4500
001 1666609
005 20220608205849.0
008 950522t19951995gw a b 001 0 eng d
020 $a3540582363 (Berlin)
020 $a0387582363 (New York)
035 $a(OCoLC)ocm32517354
035 $9AKT1272CU
035 $a(NNC)1666609
035 $a1666609
040 $aGZM$cGZM$dTMV$dTJM$dOrLoB
245 00 $aGene silencing in higher plants and related phenomena in other eukaryotes /$cedited by P. Meyer.
260 $aBerlin ;$aNew York :$bSpringer-Verlag,$c[1995], ©1995.
300 $aviii, 232 pages :$billustrations ;$c25 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
490 1 $aCurrent topics in microbiology and immunology,$x0070-217X ;$v197
504 $aIncludes bibliographical references and index.
505 0 $atrans-Inactivation of Homologous Sequences in Nicotiana tabacum / A. J. M. Matzke and M. A. Matzke -- DNA Methylation and Transgene Silencing in Petunia hybrida / P. Meyer -- Transgene Inactivation in Arabidopsis thaliana / O. Mittelsten Scheid -- Developmental Regulation of Co-suppression in Petunia hybrida / R. B. Flavell, M. O'Dell, M. Metzlaff, S. Bonhomme and P. D. Cluster -- Suppression of Flavonoid Flower Pigmentation Genes in Petunia hybrida by the Introduction of Antisense and Sense Genes / P. de Lange, R. van Blokland, J. M. Kooter and J. N. M. Mol -- Sense and Antisense Inactivation of Fruit Ripening Genes in Tomato / A. J. Hamilton, R. G. Fray and D. Grierson -- Co-suppression of [beta]-1,3-Glucanase Genes in Nicotiana tabacum / F. de Carvalho Niebel, P. Frendo, D. Inze, M. Cornelissen and M. Van Montagu -- Gene Silencing in Transgenic Plants: A Heuristic Autoregulation Model / F. Meins, Jr. and C. Kunz.
505 8 $aParamutation in Maize and Related Allelic Interaction / G. I. Patterson and V. L. Chandler -- DNA Methylation and Activity of the Maize Spm Transposable Element / N. V. Fedoroff -- Genetic and Epigenetic Inactivation of Repetitive Sequences in Neurospora crassa: RIP, DNA Methylation, and Quelling / M. J. Singer and E. U. Selker -- MIP: An Epigenetic Gene Silencing Process in Ascobolus immersus / J.-L. Rossignol and G. Faugeron -- Gene Silencing in Drosophila / S. Henikoff -- Uptake of Foreign DNA by Mammalian Cells Via the Gastrointestinal Tract in Mice: Methylation of Foreign DNA - A Cellular Defense Mechanism / W. Doerfler.
520 $aIn recent years several different gene silencing phenomena have been discovered in plants. The term "gene silencing" refers to a partial or complete inactivation of the expression of endogenous genes, transposable elements and, most frequently, transgenes. In contrast to transgene inactivation reported for mammalian systems, gene silencing in plants is not limited to the transgene alone. Insertion of a transgene into the plant genome can also trigger inactivation of homologous endogenous genes.
520 8 $aThis book summarizes the most recent data on gene silencing phenomena such as transinactivation, paramutation and co-supression. Plant researchers will find this edition a valuable help in differentiating between a number of puzzling and partly contradictory gene silencing events. Readers not familiar with plant molecular biology are introduced into the relevant methods and scientific models.
520 8 $aIn addition, four review articles, written by leading experts in their field, present examples and models of gene silencing in flamentous fungi, Drosophila and mammalian systems. By providing a comparative update on gene silencing effects in different eukaryotes, this book should stimulate communication among scientists working in diverse areas of eukaryotic gene regulation.
650 2 $aDNA, Plant$xgenetics.$0https://id.nlm.nih.gov/mesh/D018744Q000235
650 2 $aGene Expression Regulation, Plant.$0https://id.nlm.nih.gov/mesh/D018506
650 2 $aGenes, Plant.$0https://id.nlm.nih.gov/mesh/D017343
650 2 $aPlants, Genetically Modified.$0https://id.nlm.nih.gov/mesh/D030821
700 1 $aMeyer, P.$q(Peter)$0http://id.loc.gov/authorities/names/n95802318
830 0 $aCurrent topics in microbiology and immunology ;$v197.$0http://id.loc.gov/authorities/names/n42036058
852 00 $boff,bio$hQR1$i.C83 v.197