MARC Record from marc_columbia

LEADER: 03482mam a2200373 a 4500
001 1676724
005 20220608211124.0
008 950731t19951995gw a b 001 0 eng d
020 $a354057901X (Berlin)
020 $a038757901X (New York)
035 $a(OCoLC)ocm32899681
035 $9AKU3595CU
035 $a(NNC)1676724
035 $a1676724
040 $aCLU$cCLU$dGZM$dOrLoB
245 00 $aTransacting functions of human retroviruses /$cedited by Irvin S.Y. Chen [and others].
260 $aBerlin ;$aNew York :$bSpringer-Verlag,$c[1995], ©1995.
300 $avi, 239 pages :$billustrations ;$c25 cm.
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
490 1 $aCurrent topics in microbiology and immunology,$x0070-217X ;$vv. 193
504 $aIncludes bibliographical references and index.
505 00 $tRegulation of Foamy Virus Gene Expression /$rA. Rethwilm --$tTransactivation of Cellular Genes by Human Retroviruses /$rJ. D. Rosenblatt, S. Miles, J. C. Gasson and D. Prager --$tRegulation of Human Immunodeficiency Virus Type 1 Gene Expression by the Transactivator Protein Tat /$rR. B. Gaynor --$tHTLV-1 Oncoprotein Tax and Cellular Transcription Factors /$rM. Yoshida, T. Suzuki, J. Fujisawa and H. Hirai --$tThe Human Immunodeficiency Virus Type 1 Rev Protein: A Pivotal Protein in the Viral Life Cycle /$rT. Hope and R. J. Pomerantz --$tThe Human Immunodeficiency Virus Type 1 Vpu Protein: Roles in Virus Release and CD4 Downregulation /$rM. Abdul Jabbar --$tViral Protein X /$rJ. C. Kappes --$tThe Pathogenic Role of Human Immunodeficiency Virus Accessory Genes in Transgenic Mice /$rB. T. Tinkle, H. Ueda and G. Jay --
505 80 $tThe Human Immunodeficiency Virus Type 1 vif Gene: The Road from an Accessory to an Essential Role in Human Immunodeficiency Virus Type 1 Replication /$rD. J. Volsky, M. J. Potash, M. Simm, P. Sova, X.-Y. Ma, W. Chao and M. Shahabuddin --$tNef /$rL. Ratner and T. M. J. Niedermann --$tThe vpr Regulatory Gene of Human Immunodeficiency Virus /$rD. N. Levy, Y. Refaeli and D. B. Weiner.
520 $aThe coding domains of simple retrovirus genomes direct the synthesis of virion proteins. Complex retroviral genomes generate in addition to virion proteins regulatory transacting proteins that are translated from multiple spliced messenger RNAs and fulfill important functions in the virus life cycle. All human retroviruses have such complex genomes.
520 8 $aThe transacting proteins of these pathogens are attractive targets for therapeutic intervention because they are viral specific, are essential for efficient virus replication and may be mediators of viral pathogenicity. In summarizing the current knowledge on the regulatory transacting proteins of human retroviruses this volume makes an important contribution toward the control of virus disease.
650 2 $aHIV-1$xgenetics.$0https://id.nlm.nih.gov/mesh/D015497Q000235
650 2 $aHuman T-lymphotropic virus 1$xgenetics.$0https://id.nlm.nih.gov/mesh/D015368Q000235
650 2 $aRetroviridae Proteins.$0https://id.nlm.nih.gov/mesh/D012191
650 2 $aGene Expression Regulation, Viral.$0https://id.nlm.nih.gov/mesh/D015967
650 2 $aTrans-Activators.$0https://id.nlm.nih.gov/mesh/D015534
700 1 $aChen, Irvin.$0http://id.loc.gov/authorities/names/nr91025235
830 0 $aCurrent topics in microbiology and immunology ;$v193.$0http://id.loc.gov/authorities/names/n42036058
852 00 $boff,bio$hQR1$i.C83 v.193