MARC Record from marc_columbia

LEADER: 04258fam a2200421 a 4500
001 1702799
005 20220608214509.0
008 930728s1994 enk b 000 0 eng c
010 $a 93031219
020 $a0521431727 (hardback)
035 $a(OCoLC)477499645
035 $a(OCoLC)ocn477499645
035 $9ALA3486CU
035 $a(NNC)1702799
035 $a1702799
040 $aDNLM/DLC$cDLC$dDLC$dNNC$dOrLoB
050 00 $aQR182$b.M39 1994
060 00 $aQW 511.1 M476s 1994
082 00 $a574.2/9/09$220
100 1 $aMazumdar, Pauline M. H.$q(Pauline Margaret Hodgson),$d1933-$0http://id.loc.gov/authorities/names/n89661281
245 10 $aSpecies and specificity :$ban interpretation of the history of immunology /$cPauline M.H. Mazumdar.
260 $aCambridge ;$aNew York :$bCambridge University Press,$c1994.
263 $a9404
300 $axiii, 457 pages :$billustrations ;$c24 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
500 $aBased on the author's thesis (Ph.D.--Johns Hopkins University, 1976)
505 00 $g1.$tThe Unitarians: Matthias Schleiden and Carl von Nageli --$g2.$tThe Linnaeans: Ferdinand Cohn and Robert Koch --$g3.$tThe Dominance of Specificity: Koch and His Adversaries --$g4.$tThe History of Nineteenth-century Bacteriology from This Point of View --$g5.$tDichotomy and Classification in the Thought of Paul Ehrlich --$g6.$tMax von Gruber and Paul Ehrlich --$g7.$tMax von Gruber and Karl Landsteiner --$g8.$tUnity, Simplicity, Continuity: The Philosophy of Ernst Mach --$g9.$tStructural and Physical Chemistry in the Late Nineteenth Century --$g10.$tEhrlich's Chemistry and Its Opponents: i. The Dissociation Theory of Arrhenius and Madsen --$g11.$tEhrlich's Chemistry and Its Opponents: ii. The Colloid Theory of Landsteiner and Pauli --$g12.$tEhrlich's Chemistry and Its Opponents: iii. The New Structural Chemistry of Landsteiner and Pick --$g13.$tThe Decline and Persistence of Ehrlich's Chemical Theory: Landsteiner Surrenders Vienna --
505 80 $g14.$tImmunology and Genetics in the Early Twentieth Century: The Receptor and the Unit-Character --$g15.$tThe Specificity of Cells and the Specificity of Proteins: Landsteiner's Temporary Compromise --$g16.$tThe Last Confrontation: The Controversy over the Rhesus System --$tConclusion: Fragment of an Agon.
520 $aIn the first hundred years of its history, immunology was mired in the problems of species and specificity both in research and in practice. The old botanical dispute about the nature of species, which has its roots in classical Western thought, reappeared in the late nineteenth century in the disputes of the bacteriologists, and subsequently of their students, the immunologists, immunochemists, and blood group geneticists. The argument centered on the question of unity and diversity.
520 8 $aProponents of unity insisted on the continuity of nature, while those of diversity emphasized the separation and definition of individual species. In the course of this controversy, Pauline Mazumdar argues, five generations of scientific protagonists waged a bitter intellectual war that defined the structure of immunological thought during the first half of the twentieth century.
520 8 $aTheir science was designed only in part to wrest an answer from nature: it was at least as important to wring an admission of defeat from their opponents.
520 8 $aOne of the key figures in the debate was the Austrian immunochemist Karl Landsteiner, whose career provides the central focus for Mazumdar's account. His unitarian views excluded him from promotion within European institutions, where the specificity and pluralism espoused by Robert Koch and Paul Ehrlich were entrenched. Landsteiner himself was forced into a kind of exile at Rockefeller University in New York.
520 8 $aThough Landsteiner won a Nobel prize for his work, his inability to gain more widespread acceptance of his views caused him to view his life as a failure.
650 0 $aImmunology$xHistory.
650 2 $aAllergy and Immunology$xhistory.$0https://id.nlm.nih.gov/mesh/D000486Q000266
650 2 $aSpecies Specificity.$0https://id.nlm.nih.gov/mesh/D013045
852 00 $boff,bio$hQR182$i.M39 1994