MARC Record from marc_columbia

LEADER: 04103pam a2200409 a 4500
001 2003292
005 20220609050044.0
008 970328t19971997nyua 001 0 eng c
010 $a 97012543
020 $a0824799828 (alk. paper)
035 $a(OCoLC)36682385
035 $a(OCoLC)ocm36682385
035 $9AMM7429CU
035 $a(NNC)2003292
035 $a2003292
040 $aDNLM/DLC$cDLC$dDLC$dOrLoB-B
050 00 $aRS431.C23$bC37 1997
060 10 $aQU 75 C26443 1997
082 00 $a615/.3$221
245 00 $aCarbohydrates in drug design /$cedited by Zbigniew J. Witczak, Karl A. Nieforth.
260 $aNew York :$bM. Dekker,$c[1997], ©1997.
300 $aix, 703 pages :$billustrations ;$c24 cm
336 $atext$btxt$2rdacontent
337 $aunmediated$bn$2rdamedia
504 $aIncludes bibliographical references and index.
505 00 $g1.$tCarbohydrates as New and Old Targets for Future Drug Design /$rZbigniew J. Witczak --$g2.$tSialic Acid Analogues As Potential Antimicrobial Agents /$rMark von Itzstein and Milton J. Kiefel --$g3.$tSialoside Mimetics and Conjugates as Anti-inflammatory Agents and Inhibitors of Flu Virus Infections /$rRene Roy --$g4.$tDesign and Synthesis of Cell Adhesion Carbohydrate Ligands/Inhibitors /$rAkira Hasegawa and Makato Kiso --$g5.$tPolysulfates: Chemistry and Potential as Antiviral Drugs /$rMyriam Witvrouw, Christophe Pannecouque and Eric De Clercq --$g6.$tCarbohydrates with Anticoagulant and Antithrombotic Properties /$rSusanne Alban --$g7.$tHeparin Oligosaccharides: New Analogues Development and Applications /$rRobert J. Linhardt and Toshihiko Toida --$g8.$tChemoenzymatic Synthesis of Optically Active myo-Inositol Polyphosphate /$rShoichiro Ozaki and Ling Lei --$g9.$tPhosphatidylinositol-Specific Phospholipase C as a Target of Rational Drug Design /$rKarol S. Bruzik --
505 80 $g10.$tCarba-Sugars as Indispensable Units of Aminocyclitol Antibiotics and Related Biologically Active Compounds /$rSeiichiro Ogawa --$g11.$tAzasugars: Chemistry and Their Biological Activity As Potential Anti-HIV Drugs /$rLeon A. G. M. van den Broek --$g12.$tSugar-Modified Pyrimidine Nucleoside Analogues with Potential Antiviral Activity /$rStanislas Czernecki and Jean M. Valery --$g13.$tCarbohydrate Templates for the Synthesis of 3'-Hetero-Nucleosides /$rJ. Warren Beach --$g14.$tSugar-Modified Anthracyclines: A Search for Drugs Able to Overcome Multidrug Resistance /$rWaldemar A. Priebe and Roman Perez-Soler --$g15.$tLincomycin: An Organic Chemistry Perspective /$rOsman Achmatowicz and Barbara Szechner --$g16.$tFungal (1-3)-[beta]-D-Glucans: Chemistry and Antitumor Activity /$rAkira Misaki and Mariko Kakuta.
520 $aThis comprehensive resource emphasizes the highly diverse and crucial role of carbohydrates as antiinflammatory, anticancer, antidiabetic, anticonvulsant, antibiotic, and antiviral agents - covering chemical properties, biological functions, state-of-the-art methodologies for synthesizing model compounds, conformational and steric effects, synthetic and enzymatic approaches, and the discovery and development of new leads in emerging fields.
520 8 $aFurnished with over 2350 references, tables, equations, and figures, this stimulating and readily accessible volume is essential for organic, medicinal, carbohydrate, and pharmaceutical chemists; biochemists; pharmacologists; glycobiologists; cancer researchers; and graduate-level students in these disciplines.
650 0 $aCarbohydrate drugs.$0http://id.loc.gov/authorities/subjects/sh97003287
650 12 $aCarbohydrates$xchemistry.$0https://id.nlm.nih.gov/mesh/D002241Q000737
650 12 $aCarbohydrates$xtherapeutic use.$0https://id.nlm.nih.gov/mesh/D002241Q000627
650 12 $aCarbohydrates$xpharmacokinetics.$0https://id.nlm.nih.gov/mesh/D002241Q000493
650 22 $aDrug Design.$0https://id.nlm.nih.gov/mesh/D015195
700 1 $aWitczak, Zbigniew J.,$d1947-$0http://id.loc.gov/authorities/names/n97801234
700 1 $aNieforth, Karl A.$0http://id.loc.gov/authorities/names/n97801235
852 00 $boff,che$hRS431.C23$iC37 1997