MARC Record from marc_columbia

LEADER: 07238cam a2200901Ia 4500
001 4241154
005 20220723225602.0
006 m o d
007 cr cn|||||||||
008 030616s2003 njua ob 001 0 eng d
035 $a(OCoLC)ocm52434286
035 $a(NNC)4241154
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020 $a1592592988$q(electronic bk.)
020 $a9781592592982$q(electronic bk.)
020 $a9781617372988$q(print)
020 $a1617372986$q(print)
020 $z1588290034$q(alk. paper)
020 $z9781588290038$q(alk. paper)
024 7 $a10.1007/978-1-59259-298-2$2doi
035 $a(OCoLC)52434286$z(OCoLC)606985648$z(OCoLC)926455426$z(OCoLC)927459043$z(OCoLC)992064102$z(OCoLC)1001491955$z(OCoLC)1012446563$z(OCoLC)1036758564$z(OCoLC)1038405154$z(OCoLC)1039533303$z(OCoLC)1078847527$z(OCoLC)1086544470
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060 4 $aWL 300$bN493734 2003
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072 7 $aPSAN$2bicssc
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049 $aZCUA
245 00 $aNeural stem cells for brain and spinal cord repair /$cedited by Tanja Zigova, Evan Y. Snyder, Paul R. Sanberg.
260 $aTotowa, N.J. :$bHumana Press,$c©2003.
300 $a1 online resource (xix, 434 pages) :$billustrations (some color)
336 $atext$btxt$2rdacontent
337 $acomputer$bc$2rdamedia
338 $aonline resource$bcr$2rdacarrier
347 $atext file$bPDF$2rda
490 1 $aContemporary neuroscience
504 $aIncludes bibliographical references and index.
520 $aAlthough neural stem cells (NSCs) have been successfully used in animal models of various neurodegenerative diseases and of brain and spinal cord injuries, their use in studies of nervous system dysfunction is still in its infancy. In Neural Stem Cells for Brain and Spinal Cord Repair, active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors (either produced intrinsically by the cells or induced to do so following genetic engineering) that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells. Comprehensive and up-to-date, Neural Stem Cells for Brain and Spinal Cord Repair provides the first systematic overview of the biological properties and functional characteristics of NSCs, as well as outlining of several possible areas of medicine and therapy where these cells may soon prove extremely helpful.
506 $3Use copy$fRestrictions unspecified$2star$5MiAaHDL
533 $aElectronic reproduction.$b[Place of publication not identified] :$cHathiTrust Digital Library,$d2010.$5MiAaHDL
538 $aMaster and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.$uhttp://purl.oclc.org/DLF/benchrepro0212$5MiAaHDL
583 1 $adigitized$c2010$hHathiTrust Digital Library$lcommitted to preserve$2pda$5MiAaHDL
588 0 $aPrint version record.
505 0 $aI: Stem Cells for and from the CNS: Their Source and Fundamental Properties -- 1 • Sources of Cells for CNS Therapy -- 2 • Neural Stem Cells and Their Plasticity -- 3 • Identification, Selection, and Use of Adult Human Oligodendrocyte Progenitor Cells -- 4 • Generation, Characterization, and Transplantation of Immortalized Human Neural Crest Stem Cells -- 5 • The Search for Neural Progenitors in Bone Marrow and Umbilical Cord Blood -- II: In Vitro and/or In Vivo Manipulations of Stem/Progenitor Cells for the CNS -- 6 • Signal Transduction Pathways That Regulate Neural Stem Cell Division and Differentiation -- 7 • Neural Stem/Progenitor Cell Clones or "Neurospheres": A Model for Understanding Neuromorphogenesis -- 8 • Neural Stem Cells and Specification of Cell Fates: Biological and Therapeutical Perspectives -- 9 • Manipulation of Neural Precursors In Situ: Potential for Brain Self-Repair -- 10 • Neural Stem Cells in the Adult Hippocampus -- III: Stem/Progenitor Cells in Representative Therapeutic Paradigms for the CNS -- 11 • Global Gene and Cell Replacement Strategies via Stem Cells -- 12 • Neural Stem Cells in and from the Spinal Cord -- 13 • Stem Cells for Spinal Cord Injury -- 14 • Spinal Ischemia-Induced Paraplegia: A Potential Therapeutical Role of Spinally GraftedNeural Precursors and Human hNT Neurons -- 15 • Utilization of Marrow Stromal Cells for Gene Transfer into the CNS -- 16 • Preclinical Basis for Use of NT2N Cells in Neural Transplantation Therapy.
650 0 $aNeurons.
650 0 $aBrain$xTransplantation.
650 0 $aStem cells.
650 0 $aCell transplantation.
650 0 $aNervous system$xRegeneration.
650 12 $aCentral Nervous System Diseases$xtherapy
650 22 $aCell Differentiation$xphysiology
650 22 $aNerve Regeneration
650 22 $aHematopoietic Stem Cell Transplantation
650 22 $aStem Cells$xphysiology
650 2 $aNeurons
650 2 $aStem Cells
650 6 $aNeurones.
650 6 $aCerveau$xGreffe.
650 6 $aCellules souches.
650 6 $aCellules$xGreffe.
650 6 $aSystème nerveux$xRégénération.
650 7 $aMEDICAL$xSurgery$xNeurosurgery.$2bisacsh
650 7 $aNervous system$xRegeneration.$2fast$0(OCoLC)fst01036139
650 7 $aBrain$xTransplantation.$2fast$0(OCoLC)fst00837678
650 7 $aCell transplantation.$2fast$0(OCoLC)fst00850240
650 7 $aNeurons.$2fast$0(OCoLC)fst01036436
650 7 $aStem cells.$2fast$0(OCoLC)fst01132975
655 0 $aElectronic books.
655 4 $aElectronic books.
700 1 $aZigova, Tanja.
700 1 $aSnyder, Evan Y.
700 1 $aSanberg, Paul R.
776 08 $iPrint version:$tNeural stem cells for brain and spinal cord repair.$dTotowa, N.J. : Humana Press, ©2003$z1588290034$w(DLC) 2002190227$w(OCoLC)48958489
830 0 $aContemporary neuroscience.
856 40 $uhttp://www.columbia.edu/cgi-bin/cul/resolve?clio4241154$zAll EBSCO eBooks
852 8 $blweb$hEBOOKS